R
Richard N. Bergman
Researcher at Cedars-Sinai Medical Center
Publications - 489
Citations - 97005
Richard N. Bergman is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 130, co-authored 477 publications receiving 91718 citations. Previous affiliations of Richard N. Bergman include University of Southern California & University of California, Los Angeles.
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Journal ArticleDOI
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.
Gail D. Baura,Don Foster,Daniel Porte,Steven E. Kahn,Richard N. Bergman,Claudio Cobelli,Michael W. Schwartz +6 more
TL;DR: Delivery of plasma insulin into the central nervous system is saturable, and is likely facilitated by an insulin-receptor mediated transport process.
Journal ArticleDOI
Accurate Assessment of β-Cell Function: The Hyperbolic Correction
TL;DR: The disposition index is a quantitative, convenient, and accurate tool in analyzing epidemiologic data and identifying incipient impaired glucose tolerance, and is likely to remain the most accurate physiologic measure for testing hypotheses and solutions to these challenges in whole organisms.
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Cecilia M. Lindgren,Iris M. Heid,Joshua C. Randall,Claudia Lamina,Valgerdur Steinthorsdottir,Lu Qi,Elizabeth K. Speliotes,Gudmar Thorleifsson,Cristen J. Willer,Blanca M. Herrera,Anne U. Jackson,Noha Lim,Paul Scheet,Nicole Soranzo,Najaf Amin,Yurii S. Aulchenko,John C. Chambers,Alexander W. Drong,Jian'an Luan,Helen N. Lyon,Fernando Rivadeneira,Serena Sanna,Nicholas J. Timpson,M. Carola Zillikens,Jing Hua Zhao,Peter Almgren,Stefania Bandinelli,Amanda J. Bennett,Richard N. Bergman,Lori L. Bonnycastle,Suzannah Bumpstead,Stephen J. Chanock,Lynn Cherkas,Peter S. Chines,Lachlan J. M. Coin,Cyrus Cooper,Gabriel Crawford,Angela Doering,Anna F. Dominiczak,Alex S. F. Doney,Shah Ebrahim,Paul Elliott,Michael R. Erdos,Karol Estrada,Luigi Ferrucci,Guido Fischer,Nita G. Forouhi,Christian Gieger,Harald Grallert,Christopher J. Groves,Scott M. Grundy,Candace Guiducci,David Hadley,Anders Hamsten,Aki S. Havulinna,Albert Hofman,Rolf Holle,John W. Holloway,Thomas Illig,Bo Isomaa,Leonie C. Jacobs,Karen A. Jameson,Pekka Jousilahti,Fredrik Karpe,Johanna Kuusisto,Jaana Laitinen,G. Mark Lathrop,Debbie A Lawlor,Massimo Mangino,Wendy L. McArdle,Thomas Meitinger,Mario A. Morken,Andrew P. Morris,Patricia B. Munroe,Narisu Narisu,Anna Nordström,Peter Nordström,Ben A. Oostra,Colin N. A. Palmer,Felicity Payne,John F. Peden,Inga Prokopenko,Frida Renström,Aimo Ruokonen,Veikko Salomaa,Manjinder S. Sandhu,Laura J. Scott,Angelo Scuteri,Kaisa Silander,Kijoung Song,Xin Yuan,Heather M. Stringham,Amy J. Swift,Tiinamaija Tuomi,Manuela Uda,Peter Vollenweider,Gérard Waeber,Chris Wallace,G. Bragi Walters,Michael N. Weedon,Jacqueline C.M. Witteman,Cuilin Zhang,Weihua Zhang,Mark J. Caulfield,Francis S. Collins,George Davey Smith,Ian N.M. Day,Paul W. Franks,Andrew T. Hattersley,Frank B. Hu,Marjo-Riitta Järvelin,Augustine Kong,Jaspal S. Kooner,Markku Laakso,Edward G. Lakatta,Vincent Mooser,Andrew D. Morris,Leena Peltonen,Nilesh J. Samani,Tim D. Spector,David P. Strachan,Toshiko Tanaka,Jaakko Tuomilehto,André G. Uitterlinden,Cornelia M. van Duijn,Nicholas J. Wareham,Dawn M. Waterworth,Michael Boehnke,Panos Deloukas,Leif Groop,David J. Hunter,Unnur Thorsteinsdottir,David Schlessinger,H.-Erich Wichmann,Timothy M. Frayling,Gonçalo R. Abecasis,Joel N. Hirschhorn,Ruth J. F. Loos,Kari Stefansson,Karen L. Mohlke,Inês Barroso +140 more
TL;DR: Vandervell Foundation and Wellcome Trust (068545/Z/02, GR072960 as discussed by the authors, GR076113, GR069224, GR086596/Z /08/Z)
Journal ArticleDOI
Insulin resistance in short children with intrauterine growth retardation.
Paul L. Hofman,Wayne S. Cutfield,Elizabeth Robinson,Richard N. Bergman,Ram K. Menon,Mark A. Sperling,Peter D. Gluckman +6 more
TL;DR: Short prepubertal IUGR children have a specific impairment in insulin sensitivity compared to their normal birth weight peers, a potential marker for the early identification and intervention in the development of late adult-onset noninsulin-dependent diabetes mellitus.
Journal ArticleDOI
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
Zari Dastani,Hivert M-F.,Hivert M-F.,N J Timpson,Perry Jrb.,Perry Jrb.,Xin Yuan,Robert A. Scott,Peter Henneman,Iris M. Heid,Jorge R. Kizer,Lyytikäinen L-P.,Christian Fuchsberger,Toshiko Tanaka,Toshiko Tanaka,Andrew P. Morris,Kerrin S. Small,Kerrin S. Small,Aaron Isaacs,Marian Beekman,Stefan Coassin,Kurt Lohman,Lu Qi,Stavroula Kanoni,Stavroula Kanoni,James S. Pankow,Uh H-W.,Ying Wu,Aurelian Bidulescu,Laura J. Rasmussen-Torvik,Greenwood Cmt.,Martin Ladouceur,Jonna L. Grimsby,Alisa K. Manning,Liu C-T.,Jaspal S. Kooner,Vincent Mooser,Peter Vollenweider,Karen Kapur,John C. Chambers,Nicholas J. Wareham,Claudia Langenberg,Rune R. Frants,K Willems-Vandijk,Ben A. Oostra,Sara M. Willems,Claudia Lamina,Thomas W. Winkler,Bruce M. Psaty,Bruce M. Psaty,Russel Tracy,Jennifer A. Brody,I Chen,J. Viikari,Mika Kähönen,Peter P. Pramstaller,David M. Evans,B. St Pourcain,Naveed Sattar,Andrew R. Wood,Stefania Bandinelli,Olga D. Carlson,Josephine M. Egan,Stefan Böhringer,D. van Heemst,Lyudmyla Kedenko,Kati Kristiansson,Nuotio M-L.,Loo B-M.,T.B. Harris,Melissa Garcia,Alka M. Kanaya,Margot Haun,Norman Klopp,Wichmann H-E.,Panos Deloukas,Panos Deloukas,E Katsareli,David Couper,Bruce Bartholow Duncan,Bruce Bartholow Duncan,M. Kloppenburg,Linda S. Adair,Judith B. Borja,James G. Wilson,Solomon K. Musani,Xiuqing Guo,Toby Johnson,Toby Johnson,Toby Johnson,Robert K. Semple,Tanya M. Teslovich,Tanya M. Teslovich,Matthew A. Allison,Susan Redline,Sarah G. Buxbaum,Karen L. Mohlke,Ingrid Meulenbelt,Christie M. Ballantyne,George Dedoussis,Frank B. Hu,Yongmei Liu,Bernhard Paulweber,Tim D. Spector,P E Slagboom,Luigi Ferrucci,Antti Jula,Markus Perola,Olli T. Raitakari,Jose C. Florez,Jose C. Florez,Jose C. Florez,Veikko Salomaa,Johan G. Eriksson,Timothy M. Frayling,Andrew A. Hicks,Terho Lehtimäki,George Davey Smith,David S. Siscovick,Florian Kronenberg,C.M. van Duijn,C.M. van Duijn,Loos Rjf.,Loos Rjf.,Dawn M. Waterworth,James B. Meigs,Josée Dupuis,Josée Dupuis,J B Richards,Benjamin F. Voight,Benjamin F. Voight,Benjamin F. Voight,Laura J. Scott,Valgerdur Steinthorsdottir,Christian Dina,Ryan P. Welch,Eleftheria Zeggini,Eleftheria Zeggini,Cornelia Huth,Yurii S. Aulchenko,Gudmar Thorleifsson,Laura J. McCulloch,Teresa Ferreira,Harald Grallert,Najaf Amin,G Wu,Cristen J. Willer,Soumya Raychaudhuri,Soumya Raychaudhuri,Steven A. McCarroll,Oliver Hofmann,Ayellet V. Segrè,Ayellet V. Segrè,M. van Hoek,M. van Hoek,Pau Navarro,Kristin G. Ardlie,Beverley Balkau,Beverley Balkau,Rafn Benediktsson,Amanda J. Bennett,Roza Blagieva,Eric Boerwinkle,Lori L. Bonnycastle,K B Boström,Bert Bravenboer,S Bumpstead,N P Burtt,Guillaume Charpentier,P S Chines,Marilyn C. Cornelis,G Crawford,G Crawford,Doney Asf.,Katherine S. Elliott,A L Elliott,Michael R. Erdos,Caroline S. Fox,Caroline S. Fox,Christopher S. Franklin,Martha Ganser,Christian Gieger,Niels Grarup,Todd Green,Todd Green,Simon J. Griffin,Christopher J. Groves,Candace Guiducci,Samy Hadjadj,Neelam Hassanali,Christian Herder,Bo Isomaa,Anne U. Jackson,Johnson Prv.,Torben Jørgensen,Kao Whl.,Augustine Kong,Peter Kraft,Johanna Kuusisto,T. Lauritzen,M Li,Aloysius G Lieverse,Cecilia M. Lindgren,Valeriya Lyssenko,Michel Marre,Thomas Meitinger,Kristian Midthjell,Mario A. Morken,Narisu Narisu,Peter M. Nilsson,Katharine R. Owen,Felicity Payne,Petersen A-K.,Carl G. P. Platou,Christine Proença,Inga Prokopenko,Wolfgang Rathmann,Nigel W. Rayner,Neil R. Robertson,Ghislain Rocheleau,Michael Roden,Mike Sampson,Richa Saxena,Richa Saxena,Richa Saxena,B M Shields,Peter Shrader,Gunnar Sigurdsson,Thomas Sparsø,Klaus Strassburger,Heather M. Stringham,Qi Sun,A J Swift,Barbara Thorand,Jean Tichet,Tiinamaija Tuomi,R. M. van Dam,T.W. van Haeften,T van Herpt,J. V. van Vliet-Ostaptchouk,G B Walters,Michael N. Weedon,Cisca Wijmenga,Jacqueline C. M. Witteman,Richard N. Bergman,Stéphane Cauchi,Francis S. Collins,Anna L. Gloyn,Ulf Gyllensten,Torben Hansen,Torben Hansen,Torben Hansen,Winston Hide,Graham A. Hitman,Albert Hofman,David J. Hunter,Kristian Hveem,Markku Laakso,A D Morris,Palmer Cna.,Palmer Cna.,Igor Rudan,Igor Rudan,Igor Rudan,Eric J.G. Sijbrands,Lincoln D. Stein,Jaakko Tuomilehto,A Uitterlinden,Mark Walker,Richard M. Watanabe,Gonçalo R. Abecasis,Bernhard O. Boehm,Harry Campbell,Mark J. Daly,Mark J. Daly,Mark J. Daly,Andrew T. Hattersley,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Inês Barroso,L Groop,Robert Sladek,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,J.F. Wilson,Thomas Illig,Philippe Froguel,Philippe Froguel,C M van Duijn,Kari Stefansson,David Altshuler,Michael Boehnke,Mark I. McCarthy,Nicole Soranzo,Nicole Soranzo,Eleanor Wheeler,Nicole L. Glazer,Nabila Bouatia-Naji,Reedik Mägi,Joshua C. Randall,Paul Elliott,Paul Elliott,Denis Rybin,Abbas Dehghan,Jouke-Jan Hottenga,Kijoung Song,Anuj Goel,Taina K. Lajunen,Alex S. F. Doney,Christine Cavalcanti-Proença,Meena Kumari,N J Timpson,Carina Zabena,Erik Ingelsson,Erik Ingelsson,Ping An,Jeffrey R. O'Connell,Jian'an Luan,A Elliott,Rosa Maria Roccasecca,François Pattou,Praveen Sethupathy,Yavuz Ariyurek,Philip J. Barter,John Beilby,Yoav Ben-Shlomo,Sven Bergmann,Sven Bergmann,Murielle Bochud,Amélie Bonnefond,Knut Borch-Johnsen,Knut Borch-Johnsen,Yvonne Böttcher,Eric J. Brunner,S J Bumpstead,Chen Y-Di.,P Chines,Robert Clarke,Coin Ljm.,Mark E. Cooper,Laura Crisponi,Day Inm.,de Geus Ejc.,Jérôme Delplanque,A C Fedson,Antje Fischer-Rosinsky,Nita G. Forouhi,MariaGrazia Franzosi,Pilar Galan,Mark O. Goodarzi,J. Graessler,Scott M. Grundy,R. Gwilliam,Göran Hallmans,Naomi Hammond,Xijing Han,Hartikainen A-L.,Caroline Hayward,S C Heath,Serge Hercberg,David R. Hillman,Aroon D. Hingorani,Jennie Hui,Joseph Hung,Joseph Hung,Marika Kaakinen,Jaakko Kaprio,Jaakko Kaprio,Y A Kesaniemi,Mika Kivimäki,Beatrice Knight,Seppo Koskinen,Peter Kovacs,K O Kyvik,G M Lathrop,Debbie A Lawlor,O Le Bacquer,Cécile Lecoeur,Yun Li,Robert W. Mahley,Massimo Mangino,María Teresa Martínez-Larrad,Jarred B. McAteer,Jarred B. McAteer,Ruth McPherson,Christa Meisinger,David Melzer,David Meyre,Braxton D. Mitchell,Sutapa Mukherjee,Silvia Naitza,Matt Neville,Marco Orrù,Ruth E. Pakyz,Giuseppe Paolisso,Cristian Pattaro,Daniel S. Pearson,J F Peden,Nancy L. Pedersen,Pfeiffer Afh.,Irene Pichler,Ozren Polasek,Danielle Posthuma,Simon C. Potter,A Pouta,M. A. Province,Kenneth Rice,Samuli Ripatti,Samuli Ripatti,Fernando Rivadeneira,Olov Rolandsson,A. Sandbaek,M Sandhu,Serena Sanna,Avan Aihie Sayer,Paul Scheet,Udo Seedorf,Stephen J. Sharp,B Shields,Gunnar Sigurðsson,Sijbrands Ejg.,Sijbrands Ejg.,Angela Silveira,Laila Simpson,Andrew B. Singleton,Nicholas L. Smith,Nicholas L. Smith,Ulla Sovio,A Swift,Holly E. Syddall,Syvänen A-C.,Anke Tönjes,A G Uitterlinden,K W van Dijk,K W van Dijk,Dhiraj Varma,Sophie Visvikis-Siest,Veronique Vitart,N Vogelzangs,N Vogelzangs,Gerard Waeber,P J Wagner,P J Wagner,P J Wagner,Andrew Walley,Kim L. Ward,Hugh Watkins,Sarah H. Wild,Gonneke Willemsen,Witteman Jcm.,Yarnell Jwg.,Diana Zelenika,Björn Zethelius,Björn Zethelius,Guangju Zhai,Jing Hua Zhao,M C Zillikens,M C Zillikens,Ingrid B. Borecki,Pierre Meneton,Magnusson Pke.,David M. Nathan,Gordon H. Williams,Kaisa Silander,Kaisa Silander,Stefan R. Bornstein,Peter Schwarz,Jochen Spranger,Fredrik Karpe,Alan R. Shuldiner,Cyrus Cooper,Manuel Serrano-Ríos,Lars Lind,Lyle J. Palmer,Lyle J. Palmer,Paul W. Franks,Shah Ebrahim,Michael Marmot,Alan F. Wright,Michael Stumvoll,Anders Hamsten,Anders Hamsten,Thomas A. Buchanan,Timo T. Valle,Jerome I. Rotter,Penninx Bwjh.,Penninx Bwjh.,Dorret I. Boomsma,Dorret I. Boomsma,Anyuan Cao,Angelo Scuteri,Angelo Scuteri,David Schlessinger,Manuela Uda,Aimo Ruokonen,Jarvelin M-R.,Leena Peltonen,V Mooser,Kiran Musunuru,Kiran Musunuru,Albert V. Smith,Andrew C. Edmondson,Ioannis M. Stylianou,Masahiro Koseki,James P. Pirruccello,James P. Pirruccello,James P. Pirruccello,Daniel I. Chasman,Christopher T. Johansen,Sigrid W. Fouchier,Gina M. Peloso,Gina M. Peloso,Maja Barbalić,Sally L. Ricketts,J. C. Bis,Mary F. Feitosa,Marju Orho-Melander,Olle Melander,Xiaohui Li,Yoon Shin Cho,Min Jin Go,Young-Jin Kim,Lee J-Y.,Taesung Park,K Kim,Xueling Sim,Ong Rt-H.,Damien C. Croteau-Chonka,Leslie A. Lange,Josh Smith,Andreas Ziegler,Weihua Zhang,Zee Ryl.,John Whitfield,John R. Thompson,Ida Surakka,Ida Surakka,J.H. Smit,Juha Sinisalo,Jan Scott,Juha Saharinen,Chiara Sabatti,Lynda M. Rose,Robert Roberts,Mark J. Rieder,Alex N. Parker,Guillaume Paré,Christopher J. O'Donnell,Christopher J. O'Donnell,Markku S. Nieminen,Deborah A. Nickerson,Grant W. Montgomery,Wendy L. McArdle,David Masson,Nicholas G. Martin,Fabio Marroni,Gavin Lucas,Robert Luben,Lokki M-L.,Guillaume Lettre,Lenore J. Launer,Edward G. Lakatta,Reijo Laaksonen,Inke R. König,Khaw K-T.,Lee M. Kaplan,Åsa Johansson,Janssens Acjw.,Wilmar Igl,G K Hovingh,Christian Hengstenberg,Aki S. Havulinna,Aki S. Havulinna,Nicholas D. Hastie,T B Harris,Talin Haritunians,Alyson Hall,L C Groop,Elena Gonzalez,Nelson B. Freimer,Jeanette Erdmann,Kenechi Ejebe,Angela Döring,Anna F. Dominiczak,Serkalem Demissie,Serkalem Demissie,U de Faire,Mark J. Caulfield,S.M. Boekholdt,Themistocles L. Assimes,Thomas Quertermous,Mark Seielstad,Tien Yin Wong,Tai E-S.,Alan B. Feranil,Christopher W. Kuzawa,Herman A. Taylor,S. Gabriel,Hilma Holm,Vilmundur Gudnason,Ronald M. Krauss,Jose M. Ordovas,Jose M. Ordovas,Patricia B. Munroe,J S Kooner,Alan R. Tall,Robert A. Hegele,Kastelein Jjp.,Eric E. Schadt,David P. Strachan,Muredach P. Reilly,Nilesh J. Samani,Heribert Schunkert,L A Cupples,M S Sandhu,Paul M. Ridker,Daniel J. Rader,Sekar Kathiresan +618 more
TL;DR: A meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease identifies novel genetic determinants of adiponectin levels, which, taken together, influence risk of T2D and markers of insulin resistance.