R
Robert E. Breeze
Researcher at University of Colorado Denver
Publications - 68
Citations - 5633
Robert E. Breeze is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Parkinson's disease & Transplantation. The author has an hindex of 28, co-authored 68 publications receiving 5367 citations. Previous affiliations of Robert E. Breeze include Columbia University & Boston Children's Hospital.
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Journal ArticleDOI
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
Curt R. Freed,Paul Greene,Robert E. Breeze,Wei-Yann Tsai,William DuMouchel,Richard Kao,Sandra Dillon,Howard Winfield,Sharon Culver,John Q. Trojanowski,David Eidelberg,Stanley Fahn +11 more
TL;DR: After improvement in the first year, dystonia and dyskinesias recurred in 15 percent of the patients who received transplants, even after reduction or discontinuation of the dose of levodopa.
Journal ArticleDOI
Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease.
Curt R. Freed,Robert E. Breeze,Neil L. Rosenberg,Stuart A. Schneck,Evelyn H. Kriek,Qi Jx,Lone T,Y B Zhang,Snyder Ja,Trent H. Wells +9 more
TL;DR: Fetal-tissue implants appear to offer long-term clinical benefit to some patients with advanced Parkinson's disease, and both immunosuppressed and nonimmunosuppression patients improved.
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Neural transplantation for the treatment of Parkinson's disease.
Anders Björklund,Stephen B. Dunnett,Patrik Brundin,Jon Stoessl,Curt R. Freed,Robert E. Breeze,Marc Levivier,Marc Peschanski,Lorenz Studer,Roger A. Barker +9 more
TL;DR: These trials showed unequivocally that human fetal dopaminergicneurons can survive and function for more than 10 years inthe striatum of patients with PD and show no signs of beingaffected by the ongoing disease process.
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Dyskinesia after fetal cell transplantation for parkinsonism: a PET study.
Yilong Ma,Yilong Ma,Andrew Feigin,Andrew Feigin,Vijay Dhawan,Vijay Dhawan,Masafumi Fukuda,Qiuhu Shi,Paul Greene,Robert E. Breeze,Stanley Fahn,Curt R. Freed,David Eidelberg,David Eidelberg +13 more
TL;DR: The findings suggest that unbalanced increases in dopaminergic function can complicate the outcome of neuronal transplantation for parkinsonism.
Journal ArticleDOI
Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year.
Curt R. Freed,Robert E. Breeze,Neil L. Rosenberg,Stuart A. Schneck,Trent H. Wells,John N. Barrett,Scott T. Grafton,S. C. Huang,David Eidelberg,David A. Rottenberg +9 more
TL;DR: Results 12 months after surgery showed 42% improvement in left-hand speed before the first morning dose of drug and 40% greater response to drug therapy, while walking speed on an all-day basis improved 17% and reaction time was unaffected.