R
Ronald G. Tompkins
Researcher at Harvard University
Publications - 531
Citations - 44641
Ronald G. Tompkins is an academic researcher from Harvard University. The author has contributed to research in topics: Burn injury & Poison control. The author has an hindex of 93, co-authored 526 publications receiving 41859 citations. Previous affiliations of Ronald G. Tompkins include University of Toronto & Tulane University.
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Journal ArticleDOI
Dynamics of cell membrane permeability changes at supraphysiological temperatures
John C. Bischof,J. Padanilam,W.H. Holmes,Robert M. Ezzell,Raphael C. Lee,Ronald G. Tompkins,Martin L. Yarmush,Mehmet Toner +7 more
TL;DR: A quantitative fluorescent microscopy system was developed to characterize the effects of supraphysiological temperatures on the plasma membrane of mouse 3T3 fibroblasts and isolated rat skeletal muscle cells, and a time-dependent permeability assumption provided a statistically better fit of the model predictions to the data than a constant permeable assumption.
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Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance
Hiroki Sugita,Masao Kaneki,Eriko Tokunaga,Michiko Sugita,Chieko Koike,Shingo Yasuhara,Ronald G. Tompkins,J. A. Jeevendra Martyn +7 more
TL;DR: An important role for iNOS is demonstrated in LPS-induced insulin resistance, evidenced by the attenuation of LPS -induced hyperglycemia and reversal of increased hepatic glucose output by aminoguanidine.
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Objective Estimates of the Probability of Death from Burn Injuries
Colleen M. Ryan,David A. Schoenfeld,William P. Thorpe,Robert L. Sheridan,Edwin H. Cassem,Ronald G. Tompkins +5 more
TL;DR: In this article, the authors conducted a retrospective review of all 1665 patients with acute burn injuries admitted from 1990 to 1994 to Massachusetts General Hospital and the Shriners Burns Institute in Boston, and developed probability estimates for the prediction of mortality based on a minimal set of well defined variables.
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The Acutely Burned Hand: Management and Outcome Based on a Ten-Year Experience with 1047 Acute Hand Burns
Robert L. Sheridan,J. Hurley,Monica A. Smith,Colleen M. Ryan,Conrado C. Bondoc,William C. Quinby,Ronald G. Tompkins,John F. Burke +7 more
TL;DR: The approach to acutely burned hands emphasizes ranging and splinting throughout hospitalization, prompt sheet autograft wound closure as soon as practical, and the selective use of axial pin fixation and flaps.
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Burn Injury Reduces Neutrophil Directional Migration Speed in Microfluidic Devices
Kathryn L. Butler,Vijayakrishnan Ambravaneswaran,Nitin Agrawal,M Bilodeau,Mehmet Toner,Ronald G. Tompkins,Shawn P. Fagan,Daniel Irimia +7 more
TL;DR: Comparisons with samples from burn patients revealed impaired directional migration speed starting as early as 24 hours after burn injury, reaching a minimum at 72–120 hours, correlated to the size of the burn injury and potentially serving as an early indicator for concurrent infections.