R
Ronald G. Tompkins
Researcher at Harvard University
Publications - 531
Citations - 44641
Ronald G. Tompkins is an academic researcher from Harvard University. The author has contributed to research in topics: Burn injury & Poison control. The author has an hindex of 93, co-authored 526 publications receiving 41859 citations. Previous affiliations of Ronald G. Tompkins include University of Toronto & Tulane University.
Papers
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Journal ArticleDOI
Management strategy in purpura fulminans with multiple organ failure in children.
TL;DR: A management strategy is suggested, the key components of which include early excision and closure of deep wounds, aggressive critical care management and long-term follow-up should delayed epiphyseal growth occur.
Journal ArticleDOI
Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver.
David M. Yarmush,Annette D. MacDonald,Brent D. Foy,Francois Berthiaume,Ronald G. Tompkins,Martin L. Yarmush +5 more
TL;DR: Calculated flux ratios suggest that burn injury results in an increase in the contribution of pyruvate to the oxaloacetate pool at the expense of non-TCA cycle sources and a dramatic increase in 13C-labeling of glucose was observed in burned rat livers.
Journal ArticleDOI
A Rabbit Model for Metabolic Studies after Burn Injury
Rey Heng Hu,Yong-Ming Yu,Yong-Ming Yu,Don Costa,V. R. Young,V. R. Young,Colleen M. Ryan,John F. Burke,Ronald G. Tompkins +8 more
TL;DR: The metabolic changes observed in this animal model can be attributed to burn injury per se and they mimic those for flow phase in burn patients, suitable for exploring mechanistic aspects of the burn-induced changes in metabolism and nutrient balance.
Journal ArticleDOI
Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients
Aman Russom,Palaniappan Sethu,Daniel Irimia,Michael N. Mindrinos,Steve E. Calvano,Iris Garcia,Celeste C. Finnerty,Cynthia L. Tannahill,Amer Abouhamze,Julie Wilhelmy,M. Cecilia Lopez,Henry V. Baker,David N. Herndon,Stephen F. Lowry,Ronald V. Maier,Ronald W. Davis,Lyle L. Moldawer,Ronald G. Tompkins,Mehmet Toner,Paul E. Bankey,Timothy R. Billiar,Bernard H. Brownstein,David G. Camp,George Casella,Irshad H. Chaudry,Mashkoor A. Choudhry,J. Perren Cobb,Asit De,Constance Elson,Bradley D. Freeman,Richard L. Gamelli,Nicole S. Gibran,Douglas Hayden,Brian G. Harbrecht,Jureta W. Horton,William J. Hubbard,Jeffrey A. Johnson,Matthew B. Klein,James A. Lederer,Tanya Logvinenko,John A. Mannick,Philip H. Mason,Grace P. McDonald-Smith,Bruce A. McKinley,Carol L. Miller-Graziano,Joseph P. Minei,Ernest E. Moore,Frederick A. Moore,Avery B. Nathens,Grant E. O'Keefe,Laurence G. Rahme,Daniel G. Remick,David A. Schoenfeld,Michael B. Shapiro,Martin G. Schwacha,Geoffrey M. Silver,Richard D. Smith,John D. Storey,H. Shaw Warren,Michael West,Wenzhong Xiao +60 more
TL;DR: The novel microfluidic approach achieves leukocyte isolation in <25 min, and the quality of nucleic acids and genome expression analysis is equivalent to or surpasses that obtained from macroscale approaches.
Book ChapterDOI
[38] Release factors: in vitro assay and purification
TL;DR: This chapter emphasizes on the method of quantitating R activity and the purification of R1 and R2, which can be purified by preparative disc gel electrophoresis with good recovery.