R
Roop K. Khar
Researcher at Hamdard University
Publications - 159
Citations - 11605
Roop K. Khar is an academic researcher from Hamdard University. The author has contributed to research in topics: Drug delivery & Drug carrier. The author has an hindex of 50, co-authored 155 publications receiving 10410 citations. Previous affiliations of Roop K. Khar include Jamia Hamdard.
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Journal ArticleDOI
Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: possible contribution of P-glycoprotein.
TL;DR: The studies not only propose a safe approach for bioavailability enhancement and reducing toxicity of irinotecan by P-gp inhibition but in another way also reiterate the significance of elucidating herb-drug interactions for future insights.
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Solid Self-Nanoemulsifying Delivery Systems as a Platform Technology for Formulation of Poorly Soluble Drugs
Tripta Bansal,Gulam Mustafa,Zeenat I. Khan,Farhaan Jalees Ahmad,Roop K. Khar,Sushama Talegaonkar +5 more
TL;DR: Formulation considerations, selection, and function of solidifying excipients; techniques of preparation; and case studies of drugs selected from different therapeutic categories of SSNEDS are discussed.
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Development and in vitro evaluation of an acid buffering bioadhesive vaginal gel for mixed vaginal infections.
TL;DR: Results of the in vitro antimicrobial study indicated that the ABBV gel had better antimicrobial action than the commercial intravaginal drug delivery systems and retention was prolonged in an ex vivo retention experiment.
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Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote
Raisuddin Ali,Gaurav K. Jain,Zeenat Iqbal,Sushma Talegaonkar,Pragati Pandit,Sunita Sule,Geena Malhotra,Roop K. Khar,Aseem Bhatnagar,Farhan Jalees Ahmad +9 more
TL;DR: In this article, the authors developed, characterized, and carried out a clinical trial with nano-atropine sulfate (nano-AS) dry powder inhaler (DPI), which may offer several advantages over the conventional intramuscular route as an emergency treatment, including ease of administration and more rapid bioavailability.
Journal Article
Characterization and in vitro assessment of paclitaxel loaded lipid nanoparticles formulated using modified solvent injection technique
TL;DR: The modified solvent injection technique used in this research proved to be a simple, easily available and effective method to produce SLNs and could be used for controlled delivery of different lipophilic drugs for cancer chemotherapy.