R
Roop K. Khar
Researcher at Hamdard University
Publications - 159
Citations - 11605
Roop K. Khar is an academic researcher from Hamdard University. The author has contributed to research in topics: Drug delivery & Drug carrier. The author has an hindex of 50, co-authored 155 publications receiving 10410 citations. Previous affiliations of Roop K. Khar include Jamia Hamdard.
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Journal ArticleDOI
Enhanced antimalarial activity of lumefantrine nanopowder prepared by wet-milling DYNO MILL technique.
Sachin Gahoi,Gaurav K. Jain,Renu Tripathi,Swaroop Kumar Pandey,Mohammed Anwar,Musarrat Husain Warsi,Mayank Singhal,Roop K. Khar,Farhan Jalees Ahmad +8 more
TL;DR: Wet-milling using DYNO MILL offers a highly effective approach to produce stable drug nanopowders and makes the Coartem therapy more effective, and LMF nanopowder shows enhanced dissolution rate attributed to nanonization of LMF.
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Effect of DC/mDC iontophoresis and terpenes on transdermal permeation of methotrexate: in vitro study.
TL;DR: Transdermal permeation of methotrexate loaded into polyacrylamide-based hydrogel patch, across mice skin was studied in vitro after pretreatment with terpenes and ethanol, alone or in combination with iontophoresis (DC/mDC).
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Gastroretentive drug delivery system of acyclovir-loaded alginate mucoadhesive microspheres: formulation and evaluation.
TL;DR: In this paper, a mucoadhesive alginate microspheres of acyclovir were prepared to prolong the gastric residence time using a simple emulsification phase separation technique.
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Mechanism of In Vitro Percutaneous Absorption Enhancement of Carvedilol by Penetration Enhancers
TL;DR: In this paper, the effect of penetration enhancers like tulsi (basil) oil, eucalyptus oil, clove oil, black cumin oil, oleic acid and Tween 80 on the percutaneous absorption of model lipophilic drug-carvedilol was investigated using excised rat abdominal skin.
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Self-nanoemulsifying lipid carrier system for enhancement of oral bioavailability of etoposide by P-glycoprotein modulation: in vitro cell line and in vivo pharmacokinetic investigation.
TL;DR: The developed SNE drug delivery system could be a valuable tool for the effective oral delivery of etoposide as it showed a higher cytotoxicity at the highest tested concentration compared to the blank SNE9 formulation and the free etopOSide.