Roop K. Khar

TL;DR: The developed formulation was found to be better in combination and can go up to the clinical evaluation and application, and good retention over the entire precorneal area for sparfloxacin nanoparticle laden in situ gel (SNG).

TL;DR: This is the first study of its kind to quantify tea tree oil concentration in the follicles by quantifying terpinen-4-ol content using high-performance thin layer chromatography.

TL;DR: In this article, a simple, sensitive, selective, precise and stability-indicating high-performance thin-layer chromatographic (HPTLC) method for densitometric determination of moxifloxacin both as a bulk drug and from pharmaceutical formulation was developed and validated as per the International Conference on Harmonization (ICH) guidelines.

TL;DR: The validated HPTLC method could be used to carry out pharmacokinetic studies of the TBS from novel drug delivery systems and the maximum plasma concentration was found to be 5875.03 ± 114 ng mL(-1), which is significantly higher than the maximum saliva concentration.

TL;DR: Curve fitting proved that the drug release from the tablets followed the Higuchi model, and in vitro bacterial inhibition studies illustrated that the released drugs were able to diffuse through agar medium, inhibiting MTZ sensitive Bacteroides fragilis.