R
Rosalinde Masereeuw
Researcher at Utrecht University
Publications - 275
Citations - 10179
Rosalinde Masereeuw is an academic researcher from Utrecht University. The author has contributed to research in topics: Kidney & Organic anion transporter 1. The author has an hindex of 49, co-authored 250 publications receiving 8255 citations. Previous affiliations of Rosalinde Masereeuw include Tohoku University & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Quantification and visualization of the transport of octreotide, a somatostatin analogue, across monolayers of cerebrovascular endothelial cells.
Ulrich Jaehde,Rosalinde Masereeuw,de Boer Ag,Gert Fricker,Nagelkerke Jf,J. Vonderscher,Douwe D. Breimer +6 more
TL;DR: Transport studies and CLSM images suggest that octreotide passes the endothelial monolayer primarily via the paracellular route without significant contribution of carrier-mediated transport.
Journal ArticleDOI
Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling.
Tacy Santana Machado,Tacy Santana Machado,Stéphane Poitevin,Pascale Paul,Nathalie McKay,Noémie Jourde-Chiche,Tristan Legris,Annick Mouly-Bandini,Françoise Dignat-George,Philippe Brunet,Rosalinde Masereeuw,Stéphane Burtey,Stéphane Burtey,Claire Cerini +13 more
TL;DR: It is suggested that uremic toxins, such as IS, through effects on drug transporters, may modify the nonrenal clearance of drugs in patients with CKD.
Journal ArticleDOI
Bioengineering Organs for Blood Detoxification
Cécile Legallais,Dooli Kim,Sylvia M. Mihaila,Milos Mihajlovic,Marina Figliuzzi,Barbara Bonandrini,Simona Salerno,Fjodor A. Yousef Yengej,Maarten B. Rookmaaker,Natalia Sanchez Romero,Pilar Sainz-Arnal,Ulysse Pereira,Mattia Pasqua,Karin G.F. Gerritsen,Marianne C. Verhaar,Andrea Remuzzi,Andrea Remuzzi,Pedro M. Baptista,Loredana De Bartolo,Rosalinde Masereeuw,Dimitrios Stamatialis +20 more
TL;DR: This review paper reviews the approaches leading to bioengineered organs fulfilling most of the native organ functions in kidney and liver organs, as well as biohybrid constructs obtained by decellularization and recellularization of animal organs.
Journal Article
Characterization of fluorescein transport in isolated proximal tubular cells of the rat: evidence for mitochondrial accumulation.
TL;DR: The uptake and accumulation of the organic anion fluorescein-sodium (Flu-Na) was investigated in freshly isolated proximal tubular cells (PTC) of the rat kidney and it is suggested that cellular uptake of both organic anions is mediated by a carrier at the basolateral membrane.
Journal ArticleDOI
Prophylactic effect of recombinant factor VIIa in factor VII deficient patients.
Natascha C.J. Mathijssen,Rosalinde Masereeuw,Kitty Verbeek,J. Maurice Lavergne,Jean-Marc Costa,Waander L. van Heerde,Irena Novakova +6 more
TL;DR: Prophylactic treatment of FVII deficient patients with rVIIa appears to be applicable, safe and successful, although the mechanism of action remains to be elucidated.