R
Roxana Gunny
Researcher at Great Ormond Street Hospital
Publications - 28
Citations - 1260
Roxana Gunny is an academic researcher from Great Ormond Street Hospital. The author has contributed to research in topics: Cortical dysplasia & Quantitative susceptibility mapping. The author has an hindex of 16, co-authored 28 publications receiving 1044 citations. Previous affiliations of Roxana Gunny include UCL Institute of Child Health & University College London.
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Journal ArticleDOI
Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study
Sudhin Thayyil,Neil J. Sebire,Neil J. Sebire,Lyn S. Chitty,Angie Wade,WK Chong,Øystein E. Olsen,Roxana Gunny,Amaka C. Offiah,Catherine M. Owens,Dawn E. Saunders,Rosemary J. Scott,Rod Jones,Wendy Norman,S Addison,Alan Bainbridge,Ernest B. Cady,Enrico De Vita,Nicola J. Robertson,Andrew M. Taylor +19 more
TL;DR: Minimally invasive autopsy has accuracy similar to that of conventional autopsy for detection of cause of death or major pathological abnormality after death in fetuses, newborns, and infants, but was less accurate in older children.
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Overlapping cortical malformations and mutations in TUBB2B and TUBA1A
Thomas D. Cushion,William B. Dobyns,Jonathan G. L. Mullins,Neil Stoodley,Seo-Kyung Chung,Andrew E. Fry,Ute Hehr,Roxana Gunny,Arthur S. Aylsworth,Prab Prabhakar,Gökhan Uyanik,Julia Rankin,Mark I. Rees,Daniela T. Pilz +13 more
TL;DR: It is proposed that the cortical malformations associated with these genes represent a recognizable tubulinopathy-associated spectrum that ranges from lissencephalic to polymicrogyric cortical dysplasias, suggesting shared pathogenic mechanisms in terms of microtubular function and interaction with microtubule-associated proteins.
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Paediatric acquired demyelinating syndromes: incidence, clinical and magnetic resonance imaging features
Michael Absoud,Ming K. Lim,Wui K. Chong,Christian de Goede,Katharine Foster,Roxana Gunny,Cheryl Hemingway,Philip Jardine,Rachel Kneen,Marcus Likeman,Ken K. Nischal,Michael Pike,Naomi Sibtain,William P Whitehouse,Carole Cummins,Evangeline Wassmer +15 more
TL;DR: A trend towards higher incidence rates of ADS in children of South Asian and Black ethnicity was observed compared with White children, and a number of MRI characteristics distinguished ADEM from CIS cases.
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Novel surface features for automated detection of focal cortical dysplasias in paediatric epilepsy
Sophie Adler,Konrad Wagstyl,Roxana Gunny,Lisa Ronan,David W. Carmichael,J. Helen Cross,Paul C. Fletcher,Torsten Baldeweg +7 more
TL;DR: A classifier using surface-based features to identify focal abnormalities of cortical development in a paediatric cohort and was correctly identified with a higher sensitivity when novel features, based on the approach for detecting local cortical changes, were included, when compared to the sensitivity using only established features.
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Post mortem magnetic resonance imaging in the fetus, infant and child: A comparative study with conventional autopsy (MaRIAS Protocol)
Sudhin Thayyil,Neil J. Sebire,Lyn S. Chitty,Angie Wade,Øystein E. Olsen,Roxana Gunny,Amaka C. Offiah,Dawn E. Saunders,Catherine M. Owens,W. K. Kling Chong,Nicola J. Robertson,Andrew M. Taylor +11 more
TL;DR: The accuracy of a minimally invasive autopsy approach using post mortem MR imaging with that of conventional autopsy in fetuses, newborns and children for detection of the major pathological abnormalities and/or determination of the cause of death is compared.