D
Dawn E. Saunders
Researcher at UCL Institute of Child Health
Publications - 97
Citations - 5509
Dawn E. Saunders is an academic researcher from UCL Institute of Child Health. The author has contributed to research in topics: Stroke & Magnetic resonance imaging. The author has an hindex of 38, co-authored 90 publications receiving 4922 citations. Previous affiliations of Dawn E. Saunders include St George's Hospital & University College London.
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Journal ArticleDOI
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Franklyn A. Howe,S. J. Barton,Simon Cudlip,Marion Stubbs,Dawn E. Saunders,Mary Murphy,Peter R. Wilkins,Kirstie S. Opstad,V. L. Doyle,Mary A. McLean,B. A. Bell,John R. Griffiths +11 more
TL;DR: Proton spectroscopy can noninvasively provide useful information on brain tumor type and grade, and quantified lipid, macromolecule, and lactate levels increased with grade of tumor, consistent with progression from hypoxia to necrosis.
Journal ArticleDOI
Cerebral venous sinus thrombosis in children: risk factors, presentation, diagnosis and outcome
Guillaume Sébire,Brahim Tabarki,Dawn E. Saunders,Inès Leroy,Raina Liesner,C. Saint-Martin,Béatrice Husson,Andrew N Williams,Angela Wade,Fenella J. Kirkham +9 more
TL;DR: Clinical presentations of CSVT, prothrombotic risk factors and other predisposing events, clinical and radiological features of brain lesions in CSVT compared with arterial stroke, and predictors of outcome were examined.
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Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study
Sudhin Thayyil,Neil J. Sebire,Neil J. Sebire,Lyn S. Chitty,Angie Wade,WK Chong,Øystein E. Olsen,Roxana Gunny,Amaka C. Offiah,Catherine M. Owens,Dawn E. Saunders,Rosemary J. Scott,Rod Jones,Wendy Norman,S Addison,Alan Bainbridge,Ernest B. Cady,Enrico De Vita,Nicola J. Robertson,Andrew M. Taylor +19 more
TL;DR: Minimally invasive autopsy has accuracy similar to that of conventional autopsy for detection of cause of death or major pathological abnormality after death in fetuses, newborns, and infants, but was less accurate in older children.
Journal ArticleDOI
Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology
Aaron G. Filler,Michel Kliot,Franklyn A. Howe,Cecil E. Hayes,Dawn E. Saunders,Robert Goodkin,B. Anthony Bell,H. Richard Winn,John R. Griffiths,Jay S. Tsuruda +9 more
TL;DR: Direct nerve imaging can demonstrate nerve continuity, distinguish intraneural from perineural masses, and localize focal nerve compressions prior to surgical exploration, thus avoiding some exploratory surgery and allowing for smaller targeted exposures when surgery is indicated.
Journal ArticleDOI
Beta-propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation
Susan J. Hayflick,Michael C. Kruer,Allison Gregory,Tobias B. Haack,Manju A Kurian,Manju A Kurian,Henry Houlden,James C. Anderson,Nathalie Boddaert,Lynn Sanford,Sami I. Harik,Vasuki Dandu,Nardo Nardocci,Giovanna Zorzi,Todd Dunaway,Mark A. Tarnopolsky,Steven Skinner,Kenton R. Holden,Steven J. Frucht,Era Hanspal,Connie Schrander-Stumpel,Cyril Mignot,Delphine Héron,Dawn E. Saunders,Margaret Kaminska,Jean-Pierre Lin,Karine Lascelles,Stephan M. Cuno,Esther Meyer,Barbara Garavaglia,Kailash P. Bhatia,Rajith de Silva,Sarah J. Crisp,Peter Lunt,Martyn Carey,John Hardy,Thomas Meitinger,Holger Prokisch,Penelope Hogarth +38 more
TL;DR: Beta-propeller protein-associated neurodegeneration, the only X-linked disorder of neurodegenersation with brain iron accumulation, is associated with de novo mutations in WDR45 and is recognizable by a unique combination of clinical, natural history and neuroimaging features.