R
Ruediger Liersch
Researcher at University of Münster
Publications - 26
Citations - 1740
Ruediger Liersch is an academic researcher from University of Münster. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 15, co-authored 21 publications receiving 1595 citations.
Papers
More filters
Journal ArticleDOI
Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60)
Michael Pfreundschuh,Joerg Schubert,Marita Ziepert,Rudolf Schmits,Martin Mohren,Eva Lengfelder,Marcel Reiser,Christina Nickenig,Michael R. Clemens,Norma Peter,Carsten Bokemeyer,Hartmut Eimermacher,Anthony D. Ho,Martin Hoffmann,Roland Mertelsmann,Lorenz Trümper,Leopold Balleisen,Ruediger Liersch,Bernd Metzner,Frank Hartmann,Bertram Glass,Viola Poeschel,Norbert Schmitz,Christian Ruebe,Alfred C. Feller,Markus Loeffler +25 more
TL;DR: In a multivariate analysis that used six cycles of CHOP-14 without rituximab as the reference, and adjusting for known prognostic factors, all three intensified regimens improved 3-year event- free survival and progression-free survival.
Journal ArticleDOI
Tumor immune escape by the loss of homeostatic chemokine expression.
Andor Pivarcsi,Anja Müller,Andreas Hippe,Juliane Rieker,Anke van Lierop,Martin Steinhoff,Stephan Seeliger,Robert Kubitza,Ulrich Pippirs,Stephan Meller,Peter Arne Gerber,Ruediger Liersch,Erich Buenemann,Enikö Sonkoly,Ulrike Wiesner,Thomas K. Hoffmann,Leonid Schneider,Roland P. Piekorz,Elaine Enderlein,Julia Reifenberger,Ulrich Peter Rohr,Rainer Haas,Petra Boukamp,Ingo Haase,Bernd Nürnberg,Thomas Ruzicka,Albert Zlotnik,Bernhard Homey +27 more
TL;DR: It is demonstrated that human keratinocyte-derived skin tumors may evade T cell-mediated antitumor immune responses by down-regulating the expression of CCL27 through the activation of epidermal growth factor receptor (EGFR)–Ras–MAPK-signaling pathways.
Journal ArticleDOI
Combination Chemotherapy With Gemcitabine Plus Oxaliplatin in Patients With Intensively Pretreated or Refractory Germ Cell Cancer: A Study of the German Testicular Cancer Study Group
Christian K. Kollmannsberger,Jörg Beyer,Ruediger Liersch,P. Schoeffski,Bernd Metzner,J. T. Hartmann,Oliver Rick,K. Stengele,K. Hohloch,C Spott,Lothar Kanz,Carsten Bokemeyer +11 more
TL;DR: Gemcitabine plus oxaliplatin demonstrates antitumor activity with acceptable toxicity in heavily pretreated patients with relapsed or cisplatin-refractory germ cell cancer, and may offer a chance of long-term survival for selected patients.
Journal ArticleDOI
S100A2 induces metastasis in non-small cell lung cancer.
Etmar Bulk,Bülent Sargin,Utz Krug,Antje Hascher,Yu Jun,Markus Knop,Claus Kerkhoff,Volker Gerke,Ruediger Liersch,Rolf M. Mesters,Marc Hotfilder,Alessandro Marra,Steffen Koschmieder,Martin Dugas,Wolfgang E. Berdel,Hubert Serve,Carsten Müller-Tidow +16 more
TL;DR: Findings identify S100A2 as a strong metastasis inducer in vivo and might be a potential biomarker as well as a novel therapeutic target in NSCLC metastasis.
Journal ArticleDOI
Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients.
Ruediger Liersch,Joachim Gerss,Christoph Schliemann,Michael Bayer,Christian Schwöppe,Christoph Biermann,Iris Appelmann,Torsten Kessler,Bob Löwenberg,Thomas Büchner,Wolfgang Hiddemann,Carsten Müller-Tidow,Wolfgang E. Berdel,Rolf M. Mesters +13 more
TL;DR: Analysis of expression and relevance of OPN in newly diagnosed AML patients from 2 large study groups provided evidence that OPN expression is an independent prognostic factor in AML.