B
Bernd Nürnberg
Researcher at University of Tübingen
Publications - 160
Citations - 9951
Bernd Nürnberg is an academic researcher from University of Tübingen. The author has contributed to research in topics: G protein & Heterotrimeric G protein. The author has an hindex of 47, co-authored 150 publications receiving 9338 citations. Previous affiliations of Bernd Nürnberg include University of Düsseldorf & Free University of Berlin.
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Journal ArticleDOI
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Daniel J. Klionsky,Hagai Abeliovich,Patrizia Agostinis,Devendra K. Agrawal,Gjumrakch Aliev,David S. Askew,Misuzu Baba,Eric H. Baehrecke,Ben A. Bahr,Andrea Ballabio,Bruce A. Bamber,Diane C. Bassham,Ettore Bergamini,Xiaoning Bi,Martine Biard-Piechaczyk,Janice S. Blum,Dale E. Bredesen,Jeffrey L. Brodsky,John H. Brumell,Ulf T. Brunk,Wilfried Bursch,Nadine Camougrand,Eduardo Cebollero,Francesco Cecconi,Yingyu Chen,Lih-Shen Chin,Augustine M.K. Choi,Charleen T. Chu,Jongkyeong Chung,Peter G.H. Clarke,Robert S. B. Clark,Steven Clarke,Corinne Clavé,John L. Cleveland,Patrice Codogno,María Isabel Colombo,Ana Coto-Montes,James M. Cregg,Ana Maria Cuervo,Jayanta Debnath,Francesca Demarchi,Patrick B. Dennis,Phillip A. Dennis,Vojo Deretic,Rodney J. Devenish,Federica Di Sano,J. Fred Dice,Marian DiFiglia,Savithramma P. Dinesh-Kumar,Clark W. Distelhorst,Mojgan Djavaheri-Mergny,Frank C. Dorsey,Wulf Dröge,Michel Dron,William A. Dunn,Michael Duszenko,N. Tony Eissa,Zvulun Elazar,Audrey Esclatine,Eeva-Liisa Eskelinen,László Fésüs,Kim D. Finley,José M. Fuentes,Juan Fueyo,Kozo Fujisaki,Brigitte Galliot,Fen-Biao Gao,David A. Gewirtz,Spencer B. Gibson,Antje Gohla,Alfred L. Goldberg,Ramon Gonzalez,Cristina González-Estévez,Sharon M. Gorski,Roberta A. Gottlieb,Dieter Häussinger,You-Wen He,Kim A. Heidenreich,Joseph A. Hill,Maria Høyer-Hansen,Xun Hu,Wei-Pang Huang,Akiko Iwasaki,Marja Jäättelä,William T. Jackson,Xuejun Jiang,Shengkan Jin,Terje Johansen,Jae U. Jung,Motoni Kadowaki,Chanhee Kang,Ameeta Kelekar,David Kessel,Jan A.K.W. Kiel,Pyo Kim Hong,Adi Kimchi,Timothy J. Kinsella,Kirill Kiselyov,Katsuhiko Kitamoto,Erwin Knecht,Masaaki Komatsu,Eiki Kominami,Seiji Kondo,Attila L. Kovács,Guido Kroemer,Chia Yi Kuan,Rakesh Kumar,Mondira Kundu,Jacques Landry,Marianne M. Laporte,Weidong Le,Huan Yao Lei,Michael J. Lenardo,Beth Levine,Andrew P. Lieberman,Kah-Leong Lim,Fu-Cheng Lin,Willisa Liou,Leroy F. Liu,Gabriel Lopez-Berestein,Carlos López-Otín,Bo Lu,Kay F. Macleod,Walter Malorni,Wim Martinet,Ken Matsuoka,Josef Mautner,Alfred J. Meijer,Alicia Meléndez,Paul A.M. Michels,Giovanni Miotto,Wilhelm P. Mistiaen,Noboru Mizushima,Baharia Mograbi,Iryna Monastyrska,Michael Moore,Paula I. Moreira,Yuji Moriyasu,Tomasz Motyl,Christian Münz,Leon Murphy,Naweed I. Naqvi,Thomas P. Neufeld,Ichizo Nishino,Ralph A. Nixon,Takeshi Noda,Bernd Nürnberg,Michinaga Ogawa,Nancy L. Oleinick,Laura J. Olsen,Bulent Ozpolat,Shoshana Paglin,Glen E. Palmer,Issidora S. Papassideri,Miles Parkes,David H. Perlmutter,George Perry,Mauro Piacentini,Ronit Pinkas-Kramarski,Mark Prescott,Tassula Proikas-Cezanne,Nina Raben,Abdelhaq Rami,Fulvio Reggiori,Bärbel Rohrer,David C. Rubinsztein,Kevin M. Ryan,Junichi Sadoshima,Hiroshi Sakagami,Yasuyoshi Sakai,Marco Sandri,Chihiro Sasakawa,Miklós Sass,Claudio Schneider,Per Ottar Seglen,Oleksandr Seleverstov,Jeffrey Settleman,John J. Shacka,Irving M. Shapiro,Andrei A. Sibirny,Elaine C.M. Silva-Zacarin,Hans-Uwe Simon,Crisfiano Simone,Anne Simonsen,Mark A. Smith,Katharina Spanel-Borowski,Vickram Srinivas,Meredith A. Steeves,Harald Stenmark,Per E. Stromhaug,Carlos S. Subauste,Seiichiro Sugimoto,David Sulzer,Toshihiko Suzuki,Michele S. Swanson,Ira Tabas,Fumihiko Takeshita,Nicholas J. Talbot,Zsolt Tallóczy,Keiji Tanaka,Kozo Tanaka,Isei Tanida,Graham S. Taylor,J. Paul Taylor,Alexei Terman,Gianluca Tettamanti,Craig B. Thompson,Michael Thumm,Aviva M. Tolkovsky,Sharon A. Tooze,Ray Truant,Lesya V. Tumanovska,Yasuo Uchiyama,Takashi Ueno,Néstor L. Uzcátegui,Ida J. van der Klei,Eva C. Vaquero,Tibor Vellai,Michael W. Vogel,Hong Gang Wang,Paul Webster,John W. Wiley,Zhijun Xi,Gutian Xiao,Joachim Yahalom,Jin Ming Yang,George S. Yap,Xiao Ming Yin,Tamotsu Yoshimori,Li Yu,Zhenyu Yue,Michisuke Yuzaki,Olga Zabirnyk,Xiaoxiang Zheng,Xiongwei Zhu,Russell L. Deter +235 more
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
Journal ArticleDOI
Cloning and characterization of a g-protein-activated human phosphoinositide-3 kinase
Borislav Stoyanov,Stefano Volinia,Theodor Hanck,Ignacio Rubio,Michael Loubtchenkov,Daria Malek,Stefka Stoyanova,Bart Vanhaesebroeck,Ritu Dhand,Bernd Nürnberg,Peter Gierschik,Klaus Seedorf,J. Justin Hsuan,Michael D. Waterfield,Reinhard Wetzker +14 more
TL;DR: The p110 gamma isotype may link signaling through G protein-coupled receptors to the generation of phosphoinositide second messengers phosphorylated in the D-3 position.
Journal ArticleDOI
Roles of Gβγ in membrane recruitment and activation of p110γ/p101 phosphoinositide 3-kinase γ
Carsten Brock,Carsten Brock,Michael Schaefer,H. Peter Reusch,Cornelia Czupalla,Cornelia Czupalla,Manuela Michalke,Karsten Spicher,Günter Schultz,Bernd Nürnberg,Bernd Nürnberg +10 more
TL;DR: It is concluded that in vivo, Gβγ activates PI3Kγ by a mechanism assigning specific roles for both PI3kγ subunits, i.e., membrane recruitment is mediated via the noncatalytic p101 subunit, and direct stimulation of G βγ with p110γ contributes to activation of PI2Kγ.
Journal ArticleDOI
PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane.
Patricia Viard,Adrian J. Butcher,Guillaume Halet,Anthony Davies,Bernd Nürnberg,Fay Heblich,Annette C. Dolphin +6 more
TL;DR: It is shown that PI3K promotes the translocation of GFP-tagged Cav channels to the plasma membrane in both COS-7 cells and neurons and is mediated by Akt/PKB and specifically requires Cavβ2 subunits.
Journal ArticleDOI
Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence.
Christina Ehrhardt,Henju Marjuki,Thorsten Wolff,Bernd Nürnberg,Oliver Planz,Stephan Pleschka,Stephan Ludwig +6 more
TL;DR: Investigation of the function of PI3K during influenza virus infection revealed that it appears to regulate a very early step during viral entry, a perfect example of a seemingly antiviral signalling component that is misused by the virus to support effective replication.