Ryan Zarychanski

TL;DR: Insufficient evidence exists to recommend plasma exchange as an adjunctive therapy for patients with sepsis or septic shock, and Rigorous randomized controlled trials evaluating clinically relevant patient-centered outcomes are required.

TL;DR: Anemia of chronic disease is a hypoproliferative anemia that develops in response to systemic illness or inflammation.

TL;DR: In elderly adults, the high-dose influenza vaccine was well-tolerated, more immunogenic, and more efficacious in preventing influenza infections than the standard-dose vaccine.

TL;DR: Current evidence supports the use of acupuncture as an alternative for traditional analgesics in patients with osteoarthritis, with significant reductions in pain intensity, improvement in functional mobility and quality of life.

TL;DR: In this article, the effect of psychological and pharmacological treatments for depression and anxiety in persons with MS was evaluated using systematic review methodology from database inception until March 25, 2015, and the results showed that depression severity improved in nine psychological trials of depression treatment (N =307; standardized mean differences (SMD) and pooled using random effects meta-analysis.