Alexis F. Turgeon

TL;DR: The routine use of pregabalin or gabapentin for the management of postoperative pain in adult patients is not supported, as no clinically significant analgesic effect for the perioperative use of gABapentinoids was observed and there was also no effect on the prevention of post operative chronic pain and a greater risk of adverse events.

TL;DR: This research presents a novel probabilistic procedure called “spot-spot analysis” that allows for real-time analysis of the response of the immune system to natural disasters.

TL;DR: In this paper, the authors conducted an open-label, randomized controlled trial of convalescent plasma for adults with COVID-19 receiving oxygen within 12 d of respiratory symptom onset ( NCT04348656 ).

TL;DR: Heparin in patients with sepsis, septic shock, and disseminated intravascular coagulation associated with infection may be associated with decreased mortality; however, the overall impact remains uncertain.

TL;DR: Insufficient evidence exists to recommend plasma exchange as an adjunctive therapy for patients with sepsis or septic shock, and Rigorous randomized controlled trials evaluating clinically relevant patient-centered outcomes are required.