R
Ryan Zarychanski
Researcher at University of Manitoba
Publications - 230
Citations - 12857
Ryan Zarychanski is an academic researcher from University of Manitoba. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 48, co-authored 193 publications receiving 9665 citations. Previous affiliations of Ryan Zarychanski include Winnipeg Regional Health Authority & McGill University.
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Journal ArticleDOI
The benefits of 24/7 in-house intensivist coverage for prolonged-stay cardiac surgery patients
Kanwal Kumar,Rohit K. Singal,Rizwan A. Manji,Ryan Zarychanski,Dean D. Bell,Darren H. Freed,Rakesh C. Arora +6 more
TL;DR: For patients requiring a prolonged ICU stay, the model of 24/7 in-house intensivist coverage was not associated with changes in ICU LOS, nor ICU and 30-day mortality, however a reduction in blood product use, ICU complications, and total hospital LOS was observed.
Journal ArticleDOI
Safety of Hydroxychloroquine among Outpatient Clinical Trial Participants for COVID-19
Sarah M Lofgren,Melanie R. Nicol,Ananta S Bangdiwala,Katelyn A Pastick,Elizabeth C Okafor,Caleb P Skipper,Matthew F Pullen,Nicole Engen,Mahsa Abassi,Darlisha A. Williams,Alanna A Nascene,Margaret L Axelrod,Sylvain A. Lother,Lauren J. MacKenzie,Glen Drobot,Nicole Marten,Matthew P. Cheng,Matthew P. Cheng,Ryan Zarychanski,Ilan S. Schwartz,Michael S Silverman,Zain Chagla,Lauren E. Kelly,Emily G. McDonald,Emily G. McDonald,Todd C. Lee,Todd C. Lee,Katherine Huppler Hullsiek,David R. Boulware,Radha Rajasingham +29 more
TL;DR: Data from 3 outpatient COVID-19 trials demonstrated that gastrointestinal side effects were common but mild with the use of hydroxychloroquine, while seriousSide effects were rare, and Randomized clinical trials, in cohorts of healthy outpatients, can safely investigate whether hydroxy chloroquine is efficacious for COIDs.
Journal ArticleDOI
Chemoradiotherapy versus radiotherapy alone in elderly patients with stage III non-small cell lung cancer: A systematic review and meta-analysis.
David E. Dawe,David Christiansen,Anand Swaminath,Peter M. Ellis,Janet Rothney,Rasheda Rabbani,Ahmed M Abou-Setta,Ryan Zarychanski,Salaheddin M. Mahmud,Salaheddin M. Mahmud +9 more
TL;DR: Treatment of stage III NSCLC patients 70 years or older with chemotherapy and radiotherapy is associated with improved overall survival compared to radiotherapy alone and CRT appears to be tolerable in fit elderly patients and represents a reasonable standard of clinical care.
Journal ArticleDOI
Resveratrol for adults with type 2 diabetes mellitus
Maya M. Jeyaraman,Nameer Al-Yousif,Amrinder Singh Mann,Vernon W. Dolinsky,Rasheda Rabbani,Ryan Zarychanski,Ahmed M Abou-Setta +6 more
TL;DR: The limited available research does not provide sufficient evidence to support any effect, beneficial or adverse, of four to five weeks of 10 mg to 1000 mg of resveratrol in adults with type 2 diabetes mellitus, and three RCTs reported that no adverse events were observed, indicating that no deaths occurred.
Journal ArticleDOI
Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials.
Cathrine Axfors,Cathrine Axfors,Perrine Janiaud,Andreas M. Schmitt,Andreas M. Schmitt,Janneke van 't Hooft,Emily R. Smith,Noah Haber,Akin Abayomi,Manal Abduljalil,Abdulkarim Abdulrahman,Yeny Acosta-Ampudia,Manuela Aguilar-Guisado,Farah Al-Beidh,Marissa M. Alejandria,Rachelle N. Alfonso,Mohammed K. Ali,Manaf AlQahtani,Alaa AlZamrooni,Juan-Manuel Anaya,Mark Angelo C. Ang,Ismael F. Aomar,Luis E. Argumanis,Alexander Averyanov,Vladimir P. Baklaushev,Olga Balionis,Thomas Benfield,Scott Berry,Nadia Birocco,Lynn B. Bonifacio,Asha C. Bowen,Asha C. Bowen,Abbie Bown,Carlos Cabello-Gutierrez,Bernardo Camacho,Adrián Camacho-Ortiz,Sally Campbell-Lee,Damon H. Cao,Ana Cardesa,Jose M. Carnate,German Jr J. Castillo,Rossana Cavallo,Fazle Rabbi Chowdhury,Forhad Hossain Chowdhury,Giovannino Ciccone,Antonella Cingolani,Fresthel Monica M. Climacosa,Veerle Compernolle,Carlo Francisco N. Cortez,Abel Costa Neto,Sergio D’Antico,James Daly,Franca Danielle,Joshua S. Davis,Francesco Giuseppe De Rosa,Justin T Denholm,Justin T Denholm,Claudia M. Denkinger,Daniel Desmecht,Juan C. Díaz-Coronado,Juan A. Díaz Ponce-Medrano,Anne Françoise Donneau,Teresita E. Dumagay,Susanna Dunachie,Cecile C. Dungog,Olufemi Erinoso,Ivy Mae S. Escasa,Lise J Estcourt,Lise J Estcourt,Amy Evans,Agnes L.M. Evasan,Christian J. Fareli,Veronica Fernandez-Sanchez,Claudia Galassi,Juan E. Gallo,Patricia J. Garcia,Patricia L. Garcia,Jesus A. Garcia,Mutien Garigliany,Elvira Garza-González,Deonne Thaddeus V. Gauiran,Paula A. Gaviria García,Jose Antonio Giron-Gonzalez,David Gómez-Almaguer,Anthony C. Gordon,Anthony C. Gordon,André Gothot,Jeser Santiago Grass Guaqueta,Cameron Green,David Grimaldi,Naomi E Hammond,Heli Harvala,Francisco M. Heralde,Jesica A. Herrick,Alisa Higgins,Thomas Hills,Thomas Hills,Jennifer Hines,Karin Holm,Ashraful Hoque,Eric Hoste,Jose M. Ignacio,Alexander V. Ivanov,Maike Janssen,Jeffrey H. Jennings,Vivekanand Jha,Vivekanand Jha,Vivekanand Jha,Ruby Anne N King,Jens Kjeldsen-Kragh,Paul Klenerman,Aditya Kotecha,Fiorella Krapp,Luciana Labanca,Emma Laing,Mona Landin-Olsson,Pierre-François Laterre,Lyn Li Lim,Jodor Lim,Oskar Ljungquist,Jorge M. Llaca-Díaz,Concepción López-Robles,Salvador López-Cárdenas,Ileana Lopez-Plaza,Josephine Anne C. Lucero,Maria Lundgren,Juan Macías,Sandy C. Maganito,Anna Flor G. Malundo,Rubén D. Manrique,Paola M. Manzini,Miguel Marcos,Ignacio Marquez,Francisco Javier Martínez-Marcos,Ana M. Mata,Colin McArthur,Zoe McQuilten,Bryan J. McVerry,David K. Menon,Geert Meyfroidt,Ma Angelina L. Mirasol,Benoît Misset,James S. Molton,Alric V. Mondragon,Diana M. Monsalve,Parastoo Moradi Choghakabodi,Susan C. Morpeth,Paul R. Mouncey,Michel Moutschen,Carsten Müller-Tidow,Erin Murphy,Tome Najdovski,Alistair Nichol,Alistair Nichol,Henrik Nielsen,Richard M. Novak,Matthew V. N. O'Sullivan,Matthew V. N. O'Sullivan,Matthew V. N. O'Sullivan,Julián Olalla,Akin Osibogun,Bodunrin Osikomaiya,Salvador Oyonarte,Juan Mauricio Pardo-Oviedo,Mahesh C. Patel,David L. Paterson,Carlos A. Peña-Perez,Ángel Augusto Pérez-Calatayud,Eduardo Perez-Alba,Anastasia Perkina,Naomi Perry,Mandana Pouladzadeh,Inmaculada Poyato,David Price,Anne Kristine H. Quero,M. Rahman,S. Rahman,Mayur Ramesh,Carolina Ramírez-Santana,Magnus Rasmussen,Megan Rees,Megan Rees,Eduardo Rego,Jason A. Roberts,Jason A. Roberts,Jason A. Roberts,David J. Roberts,David J. Roberts,Yhojan Rodríguez,Jesús Rodríguez-Baño,Benjamin A. Rogers,Manuel Rojas,Alberto Romero,Kathryn M Rowan,Fabio Saccona,Mehdi Safdarian,Maria Clariza M. Santos,Joe Sasadeusz,Joe Sasadeusz,Gitana Scozzari,Manu Shankar-Hari,Manu Shankar-Hari,Gorav Sharma,Tom Snelling,Alonso Soto,Pedrito Y. Tagayuna,Amy Tang,Geneva Tatem,Luciana Teofili,Steven Y. C. Tong,Steven Y. C. Tong,Alexis F. Turgeon,Januario D. Veloso,Balasubramanian Venkatesh,Balasubramanian Venkatesh,Balasubramanian Venkatesh,Yanet Ventura-Enriquez,Steve Webb,Steve Webb,Lothar Wiese,Christian Wikén,Erica M. Wood,Gaukhar M. Yusubalieva,Kai Zacharowski,Ryan Zarychanski,Nina Khanna,David Moher,Steven N. Goodman,John P. A. Ioannidis,Lars G. Hemkens,Lars G. Hemkens +230 more
TL;DR: In this article, the benefits of convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19, using data from all available randomized clinical trials, including unpublished and ongoing trials, were evaluated.