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Ryan Zarychanski

Researcher at University of Manitoba

Publications -  230
Citations -  12857

Ryan Zarychanski is an academic researcher from University of Manitoba. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 48, co-authored 193 publications receiving 9665 citations. Previous affiliations of Ryan Zarychanski include Winnipeg Regional Health Authority & McGill University.

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Journal ArticleDOI

White Blood Cell Count Trajectory and Mortality in Septic Shock: A Retrospective Cohort Study

Emily Rimmer, +9 more
- 29 Nov 2018 - 
TL;DR: Seven unique and clinically relevant groups of patients with septic shock are found using trajectory analysis of the WBC count, and it is found that only baseline platelet count and sex were associated with WBC trajectory.
Posted ContentDOI

Post-exposure Prophylaxis or Preemptive Therapy for SARS-Coronavirus-2: Study Protocol for a Pragmatic Randomized Controlled Trial

Sylvain A. Lother, +24 more
- 06 May 2020 - 
TL;DR: These complementary randomized control trials are innovatively designed and adequately powered to rapidly answer urgent questions regarding the effectiveness of hydroxychloroquine to reduce transmission and disease severity of COVID-19 during a pandemic.
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Marked elevation of serum ferritin associated with Anaplasma phagocytophilum infection

Andrew Walkty, +7 more
TL;DR: For patients presenting with features of hemophagocytic syndrome including a markedly elevated ferritin, infection with A. phagocytophilum should be considered in the differential diagnosis in the appropriate clinical context (i.e., at-risk geographic location, season, tick exposure) as this distinction has management implications.
Journal ArticleDOI

Acquired Hemophilia: A Ten Year Population-Based Review of Incidence Rate, Patient Demographics, and Treatment Outcomes in Manitoba, Canada

Brittany Perija, +5 more
- 02 Dec 2016 - 
TL;DR: The incidence of Acquired hemophilia A in Manitoba, Canada is slightly higher than previous estimates, and only 21% of patients had an associated comorbidity, which is lower than previous Estimates, and may reflect a bias in non-population based series.
Proceedings ArticleDOI

The PRECISE Pilot Trial: Temporal Changes In Thrombin Generation, Protein C Levels And Activated Protein C Generation In Early Septic Shock

Alison Fox-Robichaud, +11 more