R
Ryszard Nosalski
Researcher at University of Glasgow
Publications - 32
Citations - 2116
Ryszard Nosalski is an academic researcher from University of Glasgow. The author has contributed to research in topics: Endothelial dysfunction & Blood pressure. The author has an hindex of 13, co-authored 26 publications receiving 1292 citations. Previous affiliations of Ryszard Nosalski include Jagiellonian University Medical College & Jagiellonian University.
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Journal ArticleDOI
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options.
Tomasz J. Guzik,Tomasz J. Guzik,Saidi A Mohiddin,Anthony Dimarco,Vimal Patel,K Savvatis,Federica M. Marelli-Berg,Meena S. Madhur,Maciej Tomaszewski,Pasquale Maffia,Pasquale Maffia,Fulvio D'Acquisto,Stuart A. Nicklin,Ali J. Marian,Ryszard Nosalski,Ryszard Nosalski,Eleanor Murray,Bartłomiej Guzik,Colin Berry,Rhian M. Touyz,Reinhold Kreutz,Dao Wen Wang,David Bhella,Orlando Sagliocco,Filippo Crea,E. Thomson,Iain B. McInnes +26 more
TL;DR: While ACE2 is essential for viral invasion, there is no evidence that ACE inhibitors or angiotensin receptor blockers (ARBs) worsen prognosis, Hence, patients should not discontinue their use.
Journal ArticleDOI
Perivascular adipose tissue inflammation in vascular disease.
TL;DR: It is essential to develop techniques for monitoring the characteristics of PVAT and assessing its inflammation to lead to a better understanding of the early stages of vascular pathologies and the development of new therapeutic strategies focusing on perivascular adipose tissue.
Journal ArticleDOI
Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension
Tomasz Mikolajczyk,Ryszard Nosalski,Piotr Szczepaniak,Klaudia Budzyn,Grzegorz Osmenda,Dominik Skiba,Agnieszka Sagan,Jing Wu,Antony Vinh,Paul J. Marvar,Bartłomiej Guzik,Jakub Podolec,Grant R Drummond,Heinrich E. Lob,David G. Harrison,Tomasz J. Guzik +15 more
TL;DR: Mechanistically, RANTES–/– knockout protected against vascular leukocyte, and in particular T lymphocyte infiltration, which was associated with protection from endothelial dysfunction induced by Ang II, and a significant inverse correlation was observed between circulating RantES levels as a biomarker and vascular function measured as flow‐mediated dilatation.
Journal ArticleDOI
Anti-atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis
Dominik Skiba,Ryszard Nosalski,Ryszard Nosalski,Tomasz Mikolajczyk,Tomasz Mikolajczyk,Mateusz Siedlinski,Francisco J. Rios,Augusto C. Montezano,Jacek Jawień,Rafał Olszanecki,Ryszard Korbut,Marta Czesnikiewicz-Guzik,Rhian M. Touyz,Tomasz J. Guzik,Tomasz J. Guzik +14 more
TL;DR: In this article, the effects of AVE0991 on the spontaneous atherosclerosis in apolipoprotein E (ApoE)−/− mice, in the context of vascular inflammation and plaque stability, were investigated.
Journal ArticleDOI
Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.
Francisco J. Rios,ZhiGuo Zou,Adam Harvey,Katie Y. Harvey,Ryszard Nosalski,Panagiota Anyfanti,Livia L Camargo,Silvia Lacchini,Alexey G. Ryazanov,Lillia V. Ryazanova,Sarah McGrath,Tomasz J. Guzik,Carl S. Goodyear,Augusto C. Montezano,Rhian M. Touyz +14 more
TL;DR: A novel anti-inflammatory and anti-fibrotic role is identified for TRPM7 and its protective effects are mediated, in part, through Mg2+-sensitive processes.