S
S. H. P. Parakrama Karunaratne
Researcher at University of Peradeniya
Publications - 25
Citations - 885
S. H. P. Parakrama Karunaratne is an academic researcher from University of Peradeniya. The author has contributed to research in topics: Aedes aegypti & Population. The author has an hindex of 11, co-authored 25 publications receiving 741 citations. Previous affiliations of S. H. P. Parakrama Karunaratne include Institute of Fundamental Studies & Liverpool School of Tropical Medicine.
Papers
More filters
Journal ArticleDOI
Genomic analysis of detoxification genes in the mosquito Aedes aegypti
Clare Strode,Charles S. Wondji,Jean-Philippe David,Nicola J. Hawkes,Nongkran Lumjuan,David R. Nelson,David R. Drane,S. H. P. Parakrama Karunaratne,Janet Hemingway,William C. Black,Hilary Ranson +10 more
TL;DR: Annotation of the recently determined genome sequence of the major dengue vector, Aedes aegypti, reveals an abundance of detoxification genes, and an array containing unique oligonucleotide probes for these genes was constructed and compared their expression level in insecticide resistant and susceptible strains.
Journal ArticleDOI
Pathogenomics of Culex quinquefasciatus and Meta-Analysis of Infection Responses to Diverse Pathogens
Lyric C. Bartholomay,Robert M. Waterhouse,Robert M. Waterhouse,Robert M. Waterhouse,George F. Mayhew,Corey L. Campbell,Kristin Michel,Zhen Zou,Jose Luis Ramirez,Suchismita Das,Kanwal S. Alvarez,Peter Arensburger,Bart Bryant,Bart Bryant,Sinéad B. Chapman,Yuemei Dong,Sara M. Erickson,S. H. P. Parakrama Karunaratne,S. H. P. Parakrama Karunaratne,Vladimir A. Kokoza,Chinnappa D. Kodira,Patricia Pignatelli,Sang Woon Shin,Dana L. Vanlandingham,Peter W. Atkinson,Bruce W. Birren,George K. Christophides,Rollie J. Clem,Janet Hemingway,Stephen Higgs,Karyn Megy,Hilary Ranson,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Alexander S. Raikhel,Bruce M. Christensen,George Dimopoulos,Marc A. T. Muskavitch,Marc A. T. Muskavitch,Marc A. T. Muskavitch +40 more
TL;DR: Findings provide support for the hypothesis that mosquito-borne pathogens have evolved to evade innate immune responses in three vector mosquito species of major medical importance.
Journal ArticleDOI
Kinetic and Molecular Differences in the Amplified and Non-amplified Esterases from Insecticide-resistant and Susceptible Culex quinquefasciatus Mosquitoes
S. H. P. Parakrama Karunaratne,Janet Hemingway,Kamburapola G.I. Jayawardena,Vasanthi Dassanayaka,Ashley Vaughan +4 more
TL;DR: Restriction enzyme fragment analysis of C. quinquefasciatus field populations suggest that variability of the susceptible alleles may be lower than previously suggested, and small differences between the purified esterases from resistant strains may reflect mixtures of identical amplified alleles with different non-amplified alleles, which have significantly different k values.
Journal ArticleDOI
Characterization of knockdown resistance in DDT- and pyrethroid-resistant Culex quinquefasciatus populations from Sri Lanka
Charles S. Wondji,W. A. Priyanka P. de Silva,Janet Hemingway,Hilary Ranson,S. H. P. Parakrama Karunaratne +4 more
TL;DR: The presence of two mutant alleles of the sodium channel gene, the target site for both DDT and pyrethroid insecticides, and an indel in the intron downstream of the kdr mutation has implications for the reliance on single molecular diagnostics for detection of resistance in field populations.
Journal ArticleDOI
Mechanisms of acaricide resistance in the cattle tick Rhipicephalus (Boophilus) microplus in Sri Lanka.
TL;DR: Systematic and sophisticated insecticide resistance monitoring programmes and a better understanding on the mechanisms which govern resistance development are vital for future tick control programmes.