Sachio Takeno

TL;DR: This study wanted to set objective clinical criteria for the diagnosis of refractory CRS, and found that CRSwNP displays more intense eosinophilic infiltration and the presence of Th2 cytokines.

TL;DR: It is suggested that this species-specific preparation with selective IHC loss will provide a valuable tool for studying the role of OHCs in both afferent and efferent cochlear function, and indicate a high degree of independence between the inner and outer hair cell systems in the coChlear transduction mechanism.

TL;DR: NOS was expressed in the nasal epithelium, submucosal glands, nerve fibres and the endothelium in specimens of both allergic and control groups, and the staining of epithelial cells and inflammatory cells was more marked in the allergic group than the controls.

TL;DR: Investigating differences in the ability of induction of nitric oxide synthase (NOS) isoforms by nasal epithelial cells to investigate changes to the NO production by these cells in relation to allergic rhinitis.

TL;DR: Carboplatin in this animal model predominantly affected the inner hair cells, which may provide an important model for the study of selective loss of the main afferent input in the auditory system.