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Salvador Huitron-Resendiz

Researcher at Scripps Research Institute

Publications -  52
Citations -  3628

Salvador Huitron-Resendiz is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Feline immunodeficiency virus & Simian immunodeficiency virus. The author has an hindex of 26, co-authored 51 publications receiving 3319 citations.

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Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

TL;DR: It is proposed that hcrt receptor 1 in the LC is a key target for REM sleep regulation and might be involved in the pathophysiological mechanisms of narcolepsy.
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Neuropeptide S: A Neuropeptide Promoting Arousal and Anxiolytic-like Effects

TL;DR: It is reported that a neuropeptide, NPS, potently modulates wakefulness and could also regulate anxiety, and it is shown that the LC region encompasses distinct nuclei expressing different arousal-promoting neurotransmitters.
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Transgenic mice with a reduced core body temperature have an increased life span

TL;DR: It is reported that transgenic mice engineered to overexpress the uncoupling protein 2 in hypocretin neurons (Hcrt-UCP2) have elevated hypothalamic temperature, and modest, sustained reduction of core body temperature prolonged life span independent of altered diet or CR.
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5-HT7 Receptor Inhibition and Inactivation Induce Antidepressantlike Behavior and Sleep Pattern

TL;DR: The 5-HT7 receptor might have a role in mood disorders and antagonists might have therapeutic value as antidepressants, suggesting that it utilizes an independent mechanism.
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Astrocytes contribute to gamma oscillations and recognition memory.

TL;DR: It is shown that astrocytes contribute to the fast dynamics of neural circuits that underlie normal cognitive behaviors and to maintain functional gamma oscillations both in vitro and in awake-behaving animals.