S
Samantha D. Creighton
Researcher at University of Guelph
Publications - 19
Citations - 271
Samantha D. Creighton is an academic researcher from University of Guelph. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 14 publications receiving 148 citations. Previous affiliations of Samantha D. Creighton include University of Toronto.
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Journal ArticleDOI
Dissociable cognitive impairments in two strains of transgenic Alzheimer’s disease mice revealed by a battery of object-based tests
Samantha D. Creighton,Ari L. Mendell,Daniel Palmer,Bettina E. Kalisch,Neil J. MacLusky,Vania F. Prado,Marco A. M. Prado,Boyer D. Winters +7 more
TL;DR: The current results support the use of carefully designed object-based test batteries to clarify the relationship between “object recognition” impairments and specific aspects of AD pathology in rodent models.
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MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment.
Flavio H. Beraldo,Daniel Palmer,Daniel Palmer,Sara Memar,David I. Wasserman,David I. Wasserman,Wai Jane V. Lee,Shuai Liang,Samantha D. Creighton,Benjamin Kolisnyk,Matthew F. Cowan,Justin Mels,Talal S. Masood,Chris Fodor,Mohammed A. Al-Onaizi,Robert Bartha,Tom Gee,Lisa M. Saksida,Timothy J. Bussey,Stephen S. Strother,Stephen S. Strother,Vania F. Prado,Boyer D. Winters,Marco A. M. Prado +23 more
TL;DR: An integration of touchscreen cognitive testing with an open-access database public repository, as well as a Web platform for knowledge dissemination, envision that these new platforms will enhance sharing of protocols, data availability and transparency, allowing meta-analysis and reuse of mouse cognitive data to increase the replicability/reproducibility of datasets.
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Differential contributions of de novo and maintenance DNA methyltransferases to object memory processing in the rat hippocampus and perirhinal cortex – a double dissociation
Krista A. Mitchnick,Samantha D. Creighton,Matthew O'Hara,Bettina E. Kalisch,Boyer D. Winters +4 more
TL;DR: Results reinforce the established functional double dissociation between the HPC and PRh and imply the operation of different epigenetic mechanisms in brain regions dedicated to long‐term memory processing for different types of information.
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Dissociable involvement of estrogen receptors in perirhinal cortex-mediated object-place memory in male rats.
Krista A. Mitchnick,Ari L. Mendell,Cassidy E. Wideman,Kristen H. Jardine,Samantha D. Creighton,Anne-Marie Muller,Elena Choleris,Neil J. MacLusky,Boyer D. Winters +8 more
TL;DR: Assessment of the role of 17-βestradiol (E2), ERα, ERβ, GPER, and their downstream signaling pathways, in PRh-mediated object-in-place (OiP) memory in gonadally-intact male rats reveals interesting dissociations between the roles of various ERs.
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Effects of vapourized THC and voluntary alcohol drinking during adolescence on cognition, reward, and anxiety-like behaviours in rats
Shahnaza Hamidullah,Claudia D. Lutelmowski,Samantha D. Creighton,Karling R. Luciani,Jude A. Frie,Boyer D. Winters,Jibran Y. Khokhar +6 more
TL;DR: The results show that although adolescent THC exposure acutely affects alcohol drinking, adolescent alcohol and cannabis co-use may not produce long-term additive effects.