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Sandra L. Schmid

Researcher at University of Texas Southwestern Medical Center

Publications -  209
Citations -  32222

Sandra L. Schmid is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Endocytosis & Dynamin. The author has an hindex of 89, co-authored 209 publications receiving 30096 citations. Previous affiliations of Sandra L. Schmid include University of British Columbia & Stanford University.

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Journal ArticleDOI

A cell-free biochemical complementation assay reveals complex and redundant cytosolic requirements for LRP endocytosis.

TL;DR: The in vitro reconstitution system and a new biochemical complementation assay suggest that LRP, which bears several distinct endocytic motifs in its cytoplasmic domain, may use multiple pathways for endocytosis in vitro.
Book ChapterDOI

Regulation of ATP-Dependent Endosome Acidification

TL;DR: The only known mechanism underlying molecular sorting in endosomes is their slightly acidic internal pH due to the activity of a proton ATPase present in the endosomal membrane.
Journal ArticleDOI

Not just Salk.

TL;DR: In her Science Insider News Story “Salk Institute hit with discrimination lawsuit by third female scientist” (20 July, ) M. Wadman reports that three of the four senior women scientists at the Salk Institute have filed a lawsuit alleging gender discrimination.
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The Palade Symposium: Celebrating Cell Biology at Its Best

TL;DR: A symposium was held at the University of California, San Diego, to honor the contributions of Nobel Laureate, George Palade, to cell biology as mentioned in this paper, which showcased the multidisciplinary nature, diversity, and vitality of cell biology.
Journal ArticleDOI

Intrapolypeptide interactions between the GTPase effector domain (GED) and the GTPase domain form the bundle signaling element in dynamin dimers.

TL;DR: Dynamin is not domain-swapped and that GED–GTPase domain interactions occur in cis, by cross-linking several cysteine pair replacements and analyzing cross-linked species by matrix-assisted laser desorption ionization Mega time of flight.