S
Salman M. Tajuddin
Researcher at National Institutes of Health
Publications - 56
Citations - 4510
Salman M. Tajuddin is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 26, co-authored 56 publications receiving 3445 citations. Previous affiliations of Salman M. Tajuddin include East Carolina University.
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Journal ArticleDOI
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Mary F. Feitosa,Aldi T. Kraja,Daniel I. Chasman,Yun J. Sung,Thomas W. Winkler,Ioanna Ntalla,Xiuqing Guo,Nora Franceschini,Ching-Yu Cheng,Ching-Yu Cheng,Xueling Sim,Dina Vojinovic,Jonathan Marten,Solomon K. Musani,Changwei Li,Amy R. Bentley,Michael R. Brown,Karen Schwander,Melissa A. Richard,Raymond Noordam,Hugues Aschard,Hugues Aschard,Traci M. Bartz,Lawrence F. Bielak,Rajkumar Dorajoo,Virginia Fisher,Fernando Pires Hartwig,Fernando Pires Hartwig,Andrea R. V. R. Horimoto,Kurt Lohman,Alisa K. Manning,Tuomo Rankinen,Albert V. Smith,Salman M. Tajuddin,Mary K. Wojczynski,Maris Alver,Mathilde Boissel,Qiuyin Cai,Archie Campbell,Jin-Fang Chai,Xu Chen,Jasmin Divers,Chuan Gao,Anuj Goel,Yanick Hagemeijer,Sarah E. Harris,Meian He,Fang-Chi Hsu,Anne U. Jackson,Mika Kähönen,Anuradhani Kasturiratne,Pirjo Komulainen,Brigitte Kühnel,Federica Laguzzi,Jian'an Luan,Nana Matoba,Ilja M. Nolte,Sandosh Padmanabhan,Muhammad Riaz,Muhammad Riaz,Rico Rueedi,Antonietta Robino,M. Abdullah Said,Robert A. Scott,Tamar Sofer,Alena Stančáková,Fumihiko Takeuchi,Bamidele O. Tayo,Peter J. van der Most,Tibor V. Varga,Veronique Vitart,Yajuan Wang,Erin B. Ware,Helen R. Warren,Stefan Weiss,Wanqing Wen,Lisa R. Yanek,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Saima Afaq,Najaf Amin,Marzyeh Amini,Dan E. Arking,Tin Aung,Tin Aung,Eric Boerwinkle,Eric Boerwinkle,Ingrid B. Borecki,Ulrich Broeckel,Morris J. Brown,Marco Brumat,Gregory L. Burke,Mickaël Canouil,Aravinda Chakravarti,Sabanayagam Charumathi,Sabanayagam Charumathi,Yii-Der Ida Chen,John M. C. Connell,Adolfo Correa,Lisa de las Fuentes,Renée de Mutsert,H. Janaka de Silva,Xuan Deng,Jingzhong Ding,Qing Duan,Charles B. Eaton,Georg Ehret,Ruben N. Eppinga,Evangelos Evangelou,Evangelos Evangelou,Jessica D. Faul,Stephan B. Felix,Nita G. Forouhi,Terrence Forrester,Oscar H. Franco,Yechiel Friedlander,Ilaria Gandin,He Gao,Mohsen Ghanbari,Mohsen Ghanbari,Bruna Gigante,C. Charles Gu,Dongfeng Gu,Saskia P. Hagenaars,Göran Hallmans,Tamara B. Harris,Jiang He,Sami Heikkinen,Chew-Kiat Heng,Makoto Hirata,Barbara V. Howard,M. Arfan Ikram,Ulrich John,Tomohiro Katsuya,Chiea Chuen Khor,Chiea Chuen Khor,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Woon-Puay Koh,José Eduardo Krieger,Stephen B. Kritchevsky,Michiaki Kubo,Johanna Kuusisto,Timo A. Lakka,Carl D. Langefeld,Claudia Langenberg,Lenore J. Launer,Benjamin Lehne,Cora E. Lewis,Yize Li,Shiow Lin,Jianjun Liu,Jianjun Liu,Jingmin Liu,Marie Loh,Marie Loh,Tin Louie,Reedik Mägi,Colin A. McKenzie,Thomas Meitinger,Andres Metspalu,Yuri Milaneschi,Lili Milani,Karen L. Mohlke,Yukihide Momozawa,Mike A. Nalls,Christopher P. Nelson,Christopher P. Nelson,Nona Sotoodehnia,Jill M. Norris,Jeffrey R. O'Connell,Nicholette D. Palmer,Thomas T. Perls,Nancy L. Pedersen,Annette Peters,Patricia A. Peyser,Neil Poulter,Leslie J. Raffel,Olli T. Raitakari,Kathryn Roll,Lynda M. Rose,Frits R. Rosendaal,Jerome I. Rotter,Carsten Oliver Schmidt,Pamela J. Schreiner,Nicole Schupf,William R. Scott,Peter S. Sever,Yuan Shi,Stephen Sidney,Mario Sims,Colleen M. Sitlani,Jennifer A. Smith,Harold Snieder,John M. Starr,Konstantin Strauch,Heather M. Stringham,Nicholas Y.Q. Tan,Hua Tang,Kent D. Taylor,Yik Ying Teo,Yik Ying Teo,Yih Chung Tham,Stephen Turner,André G. Uitterlinden,Peter Vollenweider,Melanie Waldenberger,Lihua Wang,Ya Xing Wang,Wen Bin Wei,Christine Williams,Jie Yao,Caizheng Yu,Jian-Min Yuan,Wei Zhao,Alan B. Zonderman,Diane M. Becker,Michael Boehnke,Donald W. Bowden,John C. Chambers,John C. Chambers,John C. Chambers,Ian J. Deary,Tõnu Esko,Tõnu Esko,Martin Farrall,Paul W. Franks,Paul W. Franks,Barry I. Freedman,Philippe Froguel,Philippe Froguel,Paolo Gasparini,Christian Gieger,Jost B. Jonas,Jost B. Jonas,Yoichiro Kamatani,Norihiro Kato,Jaspal S. Kooner,Jaspal S. Kooner,Zoltán Kutalik,Markku Laakso,Cathy C. Laurie,Karin Leander,Terho Lehtimäki,Patrik K. E. Magnusson,Albertine J. Oldehinkel,Brenda W.J.H. Penninx,Ozren Polasek,Ozren Polasek,David J. Porteous,Rainer Rauramaa,Nilesh J. Samani,Nilesh J. Samani,James Scott,Xiao-Ou Shu,Pim van der Harst,Lynne E. Wagenknecht,Nicholas J. Wareham,Hugh Watkins,David R. Weir,Ananda R. Wickremasinghe,Tangchun Wu,Wei Zheng,Claude Bouchard,Kaare Christensen,Michele K. Evans,Vilmundur Gudnason,Bernardo L. Horta,Sharon L.R. Kardia,Yongmei Liu,Alexandre C. Pereira,Bruce M. Psaty,Bruce M. Psaty,Paul M. Ridker,Rob M. van Dam,W. James Gauderman,Xiaofeng Zhu,Dennis O. Mook-Kanamori,Myriam Fornage,Charles N. Rotimi,L. Adrienne Cupples,L. Adrienne Cupples,Tanika N. Kelly,Ervin R. Fox,Caroline Hayward,Cornelia M. van Duijn,E. Shyong Tai,Tien Yin Wong,Tien Yin Wong,Charles Kooperberg,Walter Palmas,Kenneth Rice,Alanna C. Morrison,Paul Elliott,Mark J. Caulfield,Patricia B. Munroe,Dabeeru C. Rao,Michael A. Province,Daniel Levy +299 more
TL;DR: In insights into the role of alcohol consumption in the genetic architecture of hypertension, a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions is conducted.
Journal ArticleDOI
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
Eleanor Wheeler,Aaron Leong,Ching-Ti Liu,Marie-France Hivert,Rona J. Strawbridge,Clara Podmore,Clara Podmore,Man Li,Man Li,Jie Yao,Xueling Sim,Jaeyoung Hong,Audrey Y. Chu,Weihua Zhang,Weihua Zhang,Xu Wang,Peng Chen,Nisa M. Maruthur,Nisa M. Maruthur,Bianca Porneala,Stephen J. Sharp,Yucheng Jia,Edmond K. Kabagambe,Li-Ching Chang,Wei-Min Chen,Cathy E. Elks,Cathy E. Elks,Daniel S. Evans,Qiao Fan,Franco Giulianini,Min Jin Go,Jouke-Jan Hottenga,Yao Hu,Anne U. Jackson,Stavroula Kanoni,Young-Jin Kim,Marcus E. Kleber,Claes Ladenvall,Claes Ladenvall,Cecile Lecoeur,Sing-Hui Lim,Yingchang Lu,Anubha Mahajan,Carola Marzi,Mike A. Nalls,Pau Navarro,Ilja M. Nolte,Lynda M. Rose,Denis Rybin,Serena Sanna,Yuan Shi,Daniel O. Stram,Fumihiko Takeuchi,Shu Pei Tan,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Andrew Wong,Loic Yengo,Wanting Zhao,Anuj Goel,Anuj Goel,María Teresa Martínez Larrad,Dörte Radke,Perttu Salo,Perttu Salo,Toshiko Tanaka,Erik P A Van Iperen,Gonçalo R. Abecasis,Saima Afaq,Behrooz Z. Alizadeh,Alain G. Bertoni,Amélie Bonnefond,Yvonne Böttcher,Erwin P. Bottinger,Harry Campbell,Olga D. Carlson,Chien-Hsiun Chen,Chien-Hsiun Chen,Yoon Shin Cho,W. Timothy Garvey,Christian Gieger,Mark O. Goodarzi,Harald Grallert,Anders Hamsten,Catharina A. Hartman,Christian Herder,Chao A. Hsiung,Jie Huang,Michiya Igase,Masato Isono,Tomohiro Katsuya,Chiea Chuen Khor,Wieland Kiess,Katsuhiko Kohara,Peter Kovacs,Juyoung Lee,Wen-Jane Lee,Benjamin Lehne,Huaixing Li,Jianjun Liu,Jianjun Liu,Stéphane Lobbens,Jian'an Luan,Valeriya Lyssenko,Thomas Meitinger,Tetsuro Miki,Iva Miljkovic,Sanghoon Moon,Antonella Mulas,Gabriele Müller,Martina Müller-Nurasyid,Ramaiah Nagaraja,Matthias Nauck,James S. Pankow,Ozren Polasek,Ozren Polasek,Inga Prokopenko,Inga Prokopenko,Inga Prokopenko,Paula S. Ramos,Laura J. Rasmussen-Torvik,Wolfgang Rathmann,Stephen S. Rich,Neil R. Robertson,Neil R. Robertson,Michael Roden,Ronan Roussel,Ronan Roussel,Ronan Roussel,Igor Rudan,Robert A. Scott,William R. Scott,William R. Scott,Bengt Sennblad,Bengt Sennblad,David S. Siscovick,Konstantin Strauch,Liang Sun,Morris A. Swertz,Salman M. Tajuddin,Kent D. Taylor,Yik Ying Teo,Yih Chung Tham,Anke Tönjes,Nicholas J. Wareham,Gonneke Willemsen,Tom Wilsgaard,Aroon D. Hingorani,Josephine M. Egan,Luigi Ferrucci,G. Kees Hovingh,Antti Jula,Mika Kivimäki,Meena Kumari,Meena Kumari,Inger Njølstad,Colin N. A. Palmer,Manuel Serrano Ríos,Michael Stumvoll,Hugh Watkins,Hugh Watkins,Tin Aung,Matthias Blüher,Michael Boehnke,Dorret I. Boomsma,Stefan R. Bornstein,John C. Chambers,John C. Chambers,John C. Chambers,Daniel I. Chasman,Daniel I. Chasman,Yii-Der Ida Chen,Yduan-Tsong Chen,Ching-Yu Cheng,Francesco Cucca,Eco J. C. de Geus,Panos Deloukas,Panos Deloukas,Michele K. Evans,Myriam Fornage,Yechiel Friedlander,Philippe Froguel,Philippe Froguel,Leif Groop,Leif Groop,Myron D. Gross,Tamara B. Harris,Caroline Hayward,Chew-Kiat Heng,Chew-Kiat Heng,Erik Ingelsson,Erik Ingelsson,Norihiro Kato,Bong-Jo Kim,Woon-Puay Koh,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Antje Körner,Diana Kuh,Johanna Kuusisto,Markku Laakso,Xu Lin,Yongmei Liu,Ruth J. F. Loos,Patrik K. E. Magnusson,Winfried März,Winfried März,Winfried März,Mark I. McCarthy,Mark I. McCarthy,Albertine J. Oldehinkel,Ken K. Ong,Nancy L. Pedersen,Mark A. Pereira,Annette Peters,Paul M. Ridker,Charumathi Sabanayagam,Michèle M. Sale,Danish Saleheen,Juha Saltevo,Peter Eh Schwarz,Wayne Huey-Herng Sheu,Wayne Huey-Herng Sheu,Harold Snieder,Tim D. Spector,Yasuharu Tabara,Jaakko Tuomilehto,Rob M. van Dam,James G. Wilson,James F. Wilson,James F. Wilson,Bruce H. R. Wolffenbuttel,Tien Yin Wong,Jer-Yuarn Wu,Jer-Yuarn Wu,Jian-Min Yuan,Alan B. Zonderman,Nicole Soranzo,Nicole Soranzo,Nicole Soranzo,Xiuqing Guo,David J. Roberts,David J. Roberts,Jose C. Florez,Jose C. Florez,Robert Sladek,Josée Dupuis,Andrew P. Morris,Andrew P. Morris,E-Shyong Tai,Elizabeth Selvin,Elizabeth Selvin,Jerome I. Rotter,Claudia Langenberg,Inês Barroso,Inês Barroso,James B. Meigs,James B. Meigs +258 more
TL;DR: This multiancestry study recommends investigation of the possible benefits of screening for the G6PD genotype along with using HbA1c to diagnose T2D in populations of African ancestry or groups where G 6PD deficiency is common, and investigates the effect of genetic risk-scores comprised of erythrocytic or glycemic variants on incident diabetes prediction and on prevalent diabetes screening performance.
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Matthias Wuttke,Yong Li,Man Li,Karsten B. Sieber,Mary F. Feitosa,Mathias Gorski,Adrienne Tin,Lihua Wang,Audrey Y. Chu,Anselm Hoppmann,Holger Kirsten,Ayush Giri,Jin-Fang Chai,Gardar Sveinbjornsson,Bamidele O. Tayo,Teresa Nutile,Christian Fuchsberger,Jonathan Marten,Massimiliano Cocca,Sahar Ghasemi,Yizhe Xu,Katrin Horn,Damia Noce,Peter J. van der Most,Sanaz Sedaghat,Zhi Yu,Masato Akiyama,Saima Afaq,Tarunveer S. Ahluwalia,Peter Almgren,Najaf Amin,Johan Ärnlöv,Stephan J. L. Bakker,Nisha Bansal,Daniela Baptista,Sven Bergmann,Mary L. Biggs,Ginevra Biino,Michael Boehnke,Eric Boerwinkle,Mathilde Boissel,Erwin P. Bottinger,Thibaud Boutin,Hermann Brenner,Marco Brumat,Ralph Burkhardt,Adam S. Butterworth,Eric Campana,Archie Campbell,Harry Campbell,Mickaël Canouil,Robert J. Carroll,Eulalia Catamo,John C. Chambers,Miao-Ling Chee,Miao-Li Chee,Xu Chen,Ching-Yu Cheng,Yurong Cheng,Kaare Christensen,Renata Cifkova,Marina Ciullo,Maria Pina Concas,James P. Cook,Josef Coresh,Tanguy Corre,Cinzia Sala,Daniele Cusi,John Danesh,E. Warwick Daw,Martin H. de Borst,Alessandro De Grandi,Renée de Mutsert,Aiko P. J. de Vries,Frauke Degenhardt,Graciela E. Delgado,Ayse Demirkan,Emanuele Di Angelantonio,Katalin Dittrich,Jasmin Divers,Rajkumar Dorajoo,Kai-Uwe Eckardt,Georg Ehret,Paul Elliott,Karlhans Endlich,Michele K. Evans,Janine F. Felix,Valencia Hui Xian Foo,Oscar H. Franco,Andre Franke,Barry I. Freedman,Sandra Freitag-Wolf,Yechiel Friedlander,Philippe Froguel,Ron T. Gansevoort,He Gao,Paolo Gasparini,J. Michael Gaziano,Vilmantas Giedraitis,Christian Gieger,Giorgia Girotto,Franco Giulianini,Martin Gögele,Scott D. Gordon,Daniel F. Gudbjartsson,Vilmundur Gudnason,Toomas Haller,Pavel Hamet,Tamara B. Harris,Catharina A. Hartman,Caroline Hayward,Jacklyn N. Hellwege,Chew-Kiat Heng,Andrew A. Hicks,Edith Hofer,Wei Huang,Nina Hutri-Kähönen,Shih-Jen Hwang,M. Arfan Ikram,Olafur S. Indridason,Erik Ingelsson,Marcus Ising,Vincent W. V. Jaddoe,Johanna Jakobsdottir,Jost B. Jonas,Peter K. Joshi,Navya Shilpa Josyula,Bettina Jung,Mika Kähönen,Yoichiro Kamatani,Candace M. Kammerer,Masahiro Kanai,Mika Kastarinen,Shona M. Kerr,Chiea Chuen Khor,Wieland Kiess,Marcus E. Kleber,Wolfgang Koenig,Jaspal S. Kooner,Antje Körner,Peter Kovacs,Aldi T. Kraja,Alena Krajčoviechová,Holly Kramer,Bernhard K. Krämer,Florian Kronenberg,Michiaki Kubo,Brigitte Kühnel,Mikko Kuokkanen,Johanna Kuusisto,Martina La Bianca,Markku Laakso,Leslie A. Lange,Carl D. Langefeld,Jeannette Lee,Benjamin Lehne,Terho Lehtimäki,Wolfgang Lieb,Su Chi Lim,Lars Lind,Cecilia M. Lindgren,Jun Liu,Jianjun Liu,Markus Loeffler,Ruth J. F. Loos,Susanne Lucae,Mary Ann Lukas,Leo-Pekka Lyytikäinen,Reedik Mägi,Patrik K. E. Magnusson,Anubha Mahajan,Nicholas G. Martin,Jade Martins,Winfried März,Deborah Mascalzoni,Koichi Matsuda,Christa Meisinger,Thomas Meitinger,Olle Melander,Andres Metspalu,Evgenia K. Mikaelsdottir,Yuri Milaneschi,Kozeta Miliku,Pashupati P. Mishra,VA Million Veteran Program,Karen L. Mohlke,Nina Mononen,Grant W. Montgomery,Dennis O. Mook-Kanamori,Josyf C. Mychaleckyj,Girish N. Nadkarni,Mike A. Nalls,Matthias Nauck,Kjell Nikus,Boting Ning,Ilja M. Nolte,Raymond Noordam,Jeffrey R. O'Connell,Michelle L. O'Donoghue,Isleifur Olafsson,Albertine J. Oldehinkel,Marju Orho-Melander,Willem H. Ouwehand,Sandosh Padmanabhan,Nicholette D. Palmer,Runolfur Palsson,Brenda W.J.H. Penninx,Thomas T. Perls,Markus Perola,Mario Pirastu,Nicola Pirastu,Giorgio Pistis,Anna I. Podgornaia,Ozren Polasek,Belen Ponte,David J. Porteous,Tanja Poulain,Peter P. Pramstaller,Michael Preuss,Bram P. Prins,Michael A. Province,Ton J. Rabelink,Laura M. Raffield,Olli T. Raitakari,Dermot F. Reilly,Rainer Rettig,Myriam Rheinberger,Kenneth Rice,Paul M. Ridker,Fernando Rivadeneira,Federica Rizzi,David J. Roberts,Antonietta Robino,Peter Rossing,Igor Rudan,Rico Rueedi,Daniela Ruggiero,Kathleen A. Ryan,Yasaman Saba,Charumathi Sabanayagam,Veikko Salomaa,Erika Salvi,Kai-Uwe Saum,Helena Schmidt,Reinhold Schmidt,Ben Schöttker,Christina-Alexandra Schulz,Nicole Schupf,Christian M. Shaffer,Yuan Shi,Albert V. Smith,Blair H. Smith,Nicole Soranzo,Cassandra N. Spracklen,Konstantin Strauch,Heather M. Stringham,Michael Stumvoll,Per Svensson,Silke Szymczak,E-Shyong Tai,Salman M. Tajuddin,Nicholas Y. Q. Tan,Kent D. Taylor,Andrej Teren,Yih Chung Tham,Joachim Thiery,Chris H. L. Thio,Hauke Thomsen,Gudmar Thorleifsson,Daniela Toniolo,Anke Tönjes,Johanne Tremblay,Ioanna Tzoulaki,André G. Uitterlinden,Simona Vaccargiu,Rob M. van Dam,Pim van der Harst,Cornelia M. van Duijn,Digna R. Velez Edward,Niek Verweij,Suzanne Vogelezang,Uwe Völker,Peter Vollenweider,Gérard Waeber,Melanie Waldenberger,Lars Wallentin,Ya Xing Wang,Chaolong Wang,Dawn M. Waterworth,Wen Bin Wei,Harvey D. White,John Whitfield,Sarah H. Wild,James F. Wilson,Mary K. Wojczynski,Charlene A. Wong,Tien Yin Wong,Liang Xu,Qiong Yang,Masayuki Yasuda,Laura M. Yerges-Armstrong,Weihua Zhang,Alan B. Zonderman,Jerome I. Rotter,Murielle Bochud,Bruce M. Psaty,Veronique Vitart,James G. Wilson,Abbas Dehghan,Afshin Parsa,Daniel I. Chasman,Kevin Ho,Andrew P. Morris,Olivier Devuyst,Shreeram Akilesh,Sarah A. Pendergrass,Xueling Sim,Carsten A. Böger,Yukinori Okada,Todd L. Edwards,Harold Snieder,Kari Stefansson,Adriana M. Hung,Iris M. Heid,Markus Scholz,Alexander Teumer,Anna Köttgen,Cristian Pattaro +327 more
TL;DR: Trans-ancestry meta-analysis of estimated glomerular filtration rate (eGFR) from 1,046,070 individuals identifies 264 associated loci, providing a resource of molecular targets for translational research of chronic kidney disease.
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
Eleanor Wheeler,Aaron Leong,Ching-Ti Liu,Marie-France Hivert,Rona J. Strawbridge,Clara Podmore,Man Li,Jie Yao,Xueling Sim,Jaeyoung Hong,Audrey Y. Chu,Weihua Zhang,Xu Wang,Peng Chen,Nisa M. Maruthur,Bianca Porneala,Stephen J. Sharp,Yucheng Jia,Edmond K. Kabagambe,Li-Ching Chang,Wei-Min Chen,Cathy E. Elks,Daniel S. Evans,Qiao Fan,Franco Giulianini,Min Jin Go,Jouke-Jan Hottenga,Yao Hu,Anne U. Jackson,Stavroula Kanoni,Young-Jin Kim,Marcus E. Kleber,Claes Ladenvall,Cécile Lecoeur,Sing-Hui Lim,Yingchang Lu,Anubha Mahajan,Carola Marzi,Mike A. Nalls,Pau Navarro,Ilja M. Nolte,Lynda M. Rose,Denis Rybin,Serena Sanna,Yuan Shi,Daniel O. Stram,Fumihiko Takeuchi,Shu Pei Tan,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Andrew Wong,Loic Yengo,Wanting Zhao,Anuj Goel,María Teresa Martínez Larrad,Doert Radke,Perttu Salo,Toshiko Tanaka,Erik P A Van Iperen,Gonçalo R. Abecasis,Saima Afaq,Behrooz Z. Alizadeh,Alain G. Bertoni,Amelia Bonnefond,Yvonne Boettcher,Erwin P. Bottinger,Harry Campbell,Olga D. Carlson,Chien-Hsiun Chen,Yoon Shin Cho,W. Timothy Garvey,Christian Gieger,Mark O. Goodarzi,Harald Grallert,Anders Hamsten,Catharina A. Hartman,Christian Herder,Chao A. Hsiung,Jie Huang,Michiya Igase,Masato Isono,Tomohiro Katsuya,Chiea Chuen Khor,Wieland Kiess,Katsuhiko Kohara,Peter Kovacs,Juyoung Lee,Wen-Jane Lee,Benjamin Lehne,Huaixing Li,Jianjun Liu,Stéphane Lobbens,Jian'an Luang,Valeriya Lyssenko,Thomas Meitinger,Tetsuro Miki,Iva Miljkovic,Sanghoon Moon,Antonella Mulas,Gabriele Mueller,Martina Mueller-Nurasyid,Ramaiah Nagaraja,Matthias Nauck,James S. Pankow,Ozren Polasek,Inga Prokopenko,Paula S. Ramos,Laura J. Rasmussen-Torvik,Wolfgang Rathmann,Stephen S. Rich,Neil R. Robertson,Michael Roden,Ronan Roussel,Igor Rudan,Robert A. Scott,William R. Scott,Bengt Sennblad,David S. Siscovick,Konstantin Strauch,Liang Sun,Morris A. Swertz,Salman M. Tajuddin,Kent D. Taylor,Yik Ying Teo,Yih Chung Tham,Anke Toenjes,Nicholas J. Wareham,Gonneke Willemsen,Tom Wilsgaard,Aroon D. Hingorani,Josephine M. Egan,Luigi Ferrucci,G. Kees Hovingh,Antti Jula,Mika Kivimäki,Meena Kumari,Inger Njølstad,Colin N. A. Palmer,Manuel Serrano Ríos,Michael Stumvoll,Hugh Watkins,Tin Aung,Matthias Blueher,Michael Boehnke,Dorret I. Boomsma,Stefan R. Bornstein,John C. Chambers,Daniel I. Chasman,Yii-Der Ida Chen,Yduan-Tsong Chen,Ching-Yu Cheng,Francesco Cucca,Eco J. C. de Geus,Panos Deloukas,Michele K. Evans,Myriam Fornage,Yechiel Friedlander,Philippe Froguel,Leif Groop,Myron D. Gross,Tamara B. Harris,Caroline Hayward,Chew-Kiat Heng,Erik Ingelsson,Norihiro Kato,Bong-Jo Kim,Woon-Puay Koh,Jaspal S. Kooner,Antje Koerner,Diana Kuh,Johanna Kuusisto,Markku Laakso,Xu Lin,Yongmei Liu,Ruth J. F. Loos,Patrik K. E. Magnusson,Winfried Maerz,Mark I. McCarthy,Albertine J. Oldehinkel,Ken K. Ong,Nancy L. Pedersen,Mark A. Pereira,Annette Peters,Paul M. Ridker,Charumathi Sabanayagam,Michèle M. Sale,Danish Saleheen,Juha Saltevo,Peter Schwarz,Wayne Huey-Herng Sheu,Harold Snieder,Tim D. Spector,Yasuharu Tabara,Jaakko Tuomilehto,Rob M. van Dam,James G. Wilson,James F. Wilson,Bruce H. R. Wolffenbuttel,Tien Yin Wong,Jer-Yuarn Wu,Jian-Min Yuan,Alan B. Zonderman,Nicole Soranzo,Xiuqing Guo,David J. Roberts,Jose C. Florez,Robert Sladek,Josée Dupuis,Andrew P. Morris,E-Shyong Tai,Elizabeth Selvin,Jerome I. Rotter,Claudia Langenberg,Inês Barroso,James B. Meigs +214 more
TL;DR: In this article, the effect of genetic risk-scores comprised of erythrocytic or glycemic variants on incident diabetes prediction and on prevalent diabetes screening performance was investigated.
Journal ArticleDOI
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
Adrienne Tin,Jonathan Marten,Victoria L. Halperin Kuhns,Yong Li,Matthias Wuttke,Holger Kirsten,Karsten B. Sieber,Chengxiang Qiu,Mathias Gorski,Mathias Gorski,Zhi Yu,Ayush Giri,Ayush Giri,Gardar Sveinbjornsson,Man Li,Audrey Y. Chu,Anselm Hoppmann,Luke J. O’Connor,Bram P. Prins,Teresa Nutile,Damia Noce,Masato Akiyama,Massimiliano Cocca,Sahar Ghasemi,Peter J. van der Most,Katrin Horn,Yizhe Xu,Christian Fuchsberger,Sanaz Sedaghat,Saima Afaq,Saima Afaq,Najaf Amin,Johan Ärnlöv,Johan Ärnlöv,Stephan J. L. Bakker,Nisha Bansal,Daniela Baptista,Sven Bergmann,Sven Bergmann,Sven Bergmann,Mary L. Biggs,Ginevra Biino,Eric Boerwinkle,Erwin P. Bottinger,Thibaud Boutin,Marco Brumat,Ralph Burkhardt,Ralph Burkhardt,Eric Campana,Archie Campbell,Harry Campbell,Robert J. Carroll,Eulalia Catamo,John C. Chambers,Marina Ciullo,Maria Pina Concas,Josef Coresh,Tanguy Corre,Tanguy Corre,Daniele Cusi,Sala Cinzia Felicita,Martin H. de Borst,Alessandro De Grandi,Renée de Mutsert,Aiko P. J. de Vries,Graciela E. Delgado,Ayse Demirkan,Ayse Demirkan,Olivier Devuyst,Katalin Dittrich,Kai-Uwe Eckardt,Kai-Uwe Eckardt,Georg Ehret,Karlhans Endlich,Michele K. Evans,Ron T. Gansevoort,Paolo Gasparini,Vilmantas Giedraitis,Christian Gieger,Giorgia Girotto,Martin Gögele,Scott D. Gordon,Daniel F. Gudbjartsson,Vilmundur Gudnason,Toomas Haller,Pavel Hamet,Tamara B. Harris,Caroline Hayward,Andrew A. Hicks,Edith Hofer,Hilma Holm,Wei Huang,Nina Hutri-Kähönen,Shih-Jen Hwang,M. Arfan Ikram,Raychel M. Lewis,Erik Ingelsson,Johanna Jakobsdottir,Ingileif Jonsdottir,Helgi Jonsson,Peter K. Joshi,Navya Shilpa Josyula,Bettina Jung,Mika Kähönen,Yoichiro Kamatani,Masahiro Kanai,Shona M. Kerr,Wieland Kiess,Marcus E. Kleber,Wolfgang Koenig,Wolfgang Koenig,Jaspal S. Kooner,Antje Körner,Peter Kovacs,Bernhard K. Krämer,Florian Kronenberg,Michiaki Kubo,Brigitte Kühnel,Martina La Bianca,Leslie A. Lange,Benjamin Lehne,Terho Lehtimäki,Jun Liu,Jun Liu,Markus Loeffler,Ruth J. F. Loos,Leo-Pekka Lyytikäinen,Reedik Mägi,Anubha Mahajan,Anubha Mahajan,Nicholas G. Martin,Winfried März,Winfried März,Winfried März,Deborah Mascalzoni,Koichi Matsuda,Christa Meisinger,Thomas Meitinger,Andres Metspalu,Yuri Milaneschi,Christopher J. O'Donnell,Christopher J. O'Donnell,Otis D. Wilson,J. Michael Gaziano,J. Michael Gaziano,Pashupati P. Mishra,Karen L. Mohlke,Nina Mononen,Grant W. Montgomery,Dennis O. Mook-Kanamori,Martina Müller-Nurasyid,Girish N. Nadkarni,Mike A. Nalls,Matthias Nauck,Kjell Nikus,Boting Ning,Ilja M. Nolte,Raymond Noordam,Jeffrey R. O'Connell,Isleifur Olafsson,Sandosh Padmanabhan,Brenda W.J.H. Penninx,Thomas T. Perls,Annette Peters,Mario Pirastu,Nicola Pirastu,Giorgio Pistis,Ozren Polasek,Belen Ponte,David J. Porteous,Tanja Poulain,Michael Preuss,Ton J. Rabelink,Laura M. Raffield,Olli T. Raitakari,Olli T. Raitakari,Rainer Rettig,Myriam Rheinberger,Kenneth Rice,Federica Rizzi,Antonietta Robino,Igor Rudan,Alena Krajčoviechová,Renata Cifkova,Rico Rueedi,Rico Rueedi,Daniela Ruggiero,Kathleen A. Ryan,Yasaman Saba,Erika Salvi,Helena Schmidt,Reinhold Schmidt,Christian M. Shaffer,Albert V. Smith,Blair H. Smith,Cassandra N. Spracklen,Konstantin Strauch,Michael Stumvoll,Patrick Sulem,Salman M. Tajuddin,Andrej Teren,Joachim Thiery,Chris H. L. Thio,Unnur Thorsteinsdottir,Daniela Toniolo,Anke Tönjes,Johanne Tremblay,André G. Uitterlinden,Simona Vaccargiu,Pim van der Harst,Cornelia M. van Duijn,Cornelia M. van Duijn,Cornelia M. van Duijn,Niek Verweij,Uwe Völker,Peter Vollenweider,Gérard Waeber,Melanie Waldenberger,John Whitfield,Sarah H. Wild,James F. Wilson,Qiong Yang,Weihua Zhang,Weihua Zhang,Alan B. Zonderman,Murielle Bochud,James G. Wilson,Sarah A. Pendergrass,Kevin Ho,Afshin Parsa,Afshin Parsa,Peter P. Pramstaller,Bruce M. Psaty,Bruce M. Psaty,Carsten A. Böger,Harold Snieder,Adam S. Butterworth,Yukinori Okada,Todd L. Edwards,Todd L. Edwards,Kari Stefansson,Katalin Susztak,Markus Scholz,Iris M. Heid,Adriana M. Hung,Adriana M. Hung,Alexander Teumer,Cristian Pattaro,Owen M. Woodward,Veronique Vitart,Anna Köttgen,Anna Köttgen +251 more
TL;DR: A trans-ancestry genome-wide association study of serum urate levels identifies 183 loci that improve the prediction of gout in an independent cohort of 334,880 individuals, and implicates the kidney and liver as key target organs and prioritize potential causal genes.