S
Sanjay Patel
Researcher at Royal Prince Alfred Hospital
Publications - 133
Citations - 3649
Sanjay Patel is an academic researcher from Royal Prince Alfred Hospital. The author has contributed to research in topics: Medicine & Acute coronary syndrome. The author has an hindex of 26, co-authored 122 publications receiving 2426 citations. Previous affiliations of Sanjay Patel include Stanford University & University Hospital Southampton NHS Foundation Trust.
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Journal ArticleDOI
Diagnostic test accuracy of a 2-transcript host RNA signature for discriminating bacterial vs viral infection in febrile children
Jethro Herberg,Myrsini Kaforou,Victoria J. Wright,Hannah Shailes,Hariklia Eleftherohorinou,Clive J. Hoggart,Miriam Cebey-López,Michael J. Carter,Victoria A. Janes,Stuart Gormley,Chisato Shimizu,Chisato Shimizu,Adriana H. Tremoulet,Adriana H. Tremoulet,Anouk M. Barendregt,Antonio Salas,John T. Kanegaye,John T. Kanegaye,Andrew J. Pollard,Saul N. Faust,Saul N. Faust,Sanjay Patel,Taco W. Kuijpers,Federico Martinón-Torres,Jane C. Burns,Jane C. Burns,Lachlan J. M. Coin,Michael Levin +27 more
TL;DR: This study provides preliminary data regarding test accuracy of a 2-transcript host RNA signature discriminating bacterial from viral infection in febrile children.
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Colchicine Acutely Suppresses Local Cardiac Production of Inflammatory Cytokines in Patients With an Acute Coronary Syndrome.
Gonzalo Martínez,Stacy Robertson,Jennifer Y. Barraclough,Qiong Xia,Ziad Mallat,Christina A. Bursill,David S. Celermajer,Sanjay Patel +7 more
TL;DR: Assessment of the local cardiac production of inflammatory cytokines in patients with acute coronary syndromes (ACS), stable coronary artery disease and in controls determined whether acute administration of colchicine inhibits their production, and short-term colchichine administration rapidly and significantly reduces levels of these cytokines.
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The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation
TL;DR: The role of monocytes/macrophages and neutrophils in Atherosclerosis is described, mechanisms of activation of the NLRP3 inflammasome in the setting of atherosclerosis-associated inflammation are outlined and potential therapies that specifically target the NL RP3 infammasome and/or its downstream mediators in atheros sclerosis are discussed.
Journal ArticleDOI
Reconstituted high-density lipoprotein increases plasma high-density lipoprotein anti-inflammatory properties and cholesterol efflux capacity in patients with type 2 diabetes.
Sanjay Patel,Brian G. Drew,Shirley Nakhla,Stephen J. Duffy,Andrew J. Murphy,Phillip J. Barter,Kerry-Anne Rye,Jaye Chin-Dusting,Anh Hoang,Dmitri Sviridov,David S. Celermajer,David S. Celermajer,Bronwyn A. Kingwell +12 more
TL;DR: In this article, the effects of reconstituted high-density lipoprotein (rHDL) infusions on plasma anti-inflammatory properties and ex vivo cholesterol efflux in patients with type 2 diabetes were investigated.
Journal ArticleDOI
Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome: A CT Coronary Angiography Study
Kaivan Vaidya,Clare Arnott,Gonzalo Martínez,Bernard Ng,Samuel McCormack,David R. Sullivan,David S. Celermajer,Sanjay Patel +7 more
TL;DR: It is suggested, for the first time, that low-dose colchicine therapy favorably modifies coronary plaque, independent of high-dose statin intensification therapy and substantial low-density lipoprotein reduction.