S
Sanjit Kumar
Researcher at VIT University
Publications - 55
Citations - 561
Sanjit Kumar is an academic researcher from VIT University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 28 publications receiving 432 citations. Previous affiliations of Sanjit Kumar include University of Ngaoundéré & All India Institute of Medical Sciences.
Papers
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Journal ArticleDOI
Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis.
Tse Siang Kang,Dessislava Georgieva,Nikolay Genov,Mário T. Murakami,Mau Sinha,Ramasamy P. Kumar,Punit Kaur,Sanjit Kumar,Sharmistha Dey,Sujata Sharma,Alice Vrielink,Christian Betzel,Soichi Takeda,Raghuvir K. Arni,Tej P. Singh,R. Manjunatha Kini +15 more
TL;DR: The structures of inhibitor–enzyme complexes provide ideal platforms for the design of potent inhibitors which are useful in the development of prototypes and lead compounds with potential therapeutic applications.
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Molecular basis for nonspecificity of nonsteroidal anti-inflammatory drugs (NSAIDs).
TL;DR: The extensive binding of NSAIDs is responsible for their limited in vivo efficacy as well as the large spectrum of their effects, and the biochemical nature of drugs binding to multiple protein targets and its implications on physiology are discussed.
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Simultaneous inhibition of anti‐coagulation and inflammation: crystal structure of phospholipase A2 complexed with indomethacin at 1.4 Å resolution reveals the presence of the new common ligand‐binding site
Nagendra Singh,Ramasamy P. Kumar,Sanjit Kumar,Sujata Sharma,R. Mir,Punit Kaur,Alagiri Srinivasan,Tej P. Singh +7 more
TL;DR: Indomethacin is the first compound that has been shown to bind at this novel site resulting in the prevention of anti‐coagulation and inflammation.
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Myoblast differentiation and protein expression in electrospun graphene oxide (GO)-poly (ε-caprolactone, PCL) composite meshes
TL;DR: In this article, a myoblast (C2C12) differentiation on graphene oxide nanoplatelets (GO)-poly (e-caprolactone, PCL) composite scaffold meshes, prepared by electrospinning method, was reported.
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Identification of a novel and potent inhibitor of phospholipase A(2) in a medicinal plant: crystal structure at 1.93Å and Surface Plasmon Resonance analysis of phospholipase A(2) complexed with berberine.
D. Naveen Chandra,G.K. Prasanth,Nagendra Singh,Sanjit Kumar,O. Jithesh,Chittalakkottu Sadasivan,Sujatha Sharma,Tej P. Singh,M. Haridas +8 more
TL;DR: Crystal of Russell Viper venom phospholipase A(2) complexed with an isoquinoline alkaloid, berberine from a herbaceous plant Cardiospermum halicacabum, was prepared and its structure was solved by X-ray crystallography.