Santosh Nigam

TL;DR: The mechanisms for the regulation of the levels of the proposed endovanilloids, as well as their TRPV1-mediated pharmacological actions in vitro and in vivo, are discussed and the possible pathological conditions in which endovanillsoids, acting at sometimes aberrantly expressed TRPv1 receptors, might play a role are outlined.

TL;DR: It is proposed that the platelet activating factor (PAF) acetylhydrolases of type II, which cleave preferentially peroxidised or lipoxygenated phospholipids, are competent for theospholipid repair, irrespective of their role in PAF metabolism.

TL;DR: The results suggest that in the absence of IL-4, nuclear histones may be bound to regulatory elements of the 15-LOX-1 gene, preventing its transcription, although these reactions follow differential kinetics.

TL;DR: It is concluded that pharmacological enhancement of endocannabinoid levels (through inhibition of endOCannabinoid hydrolysis) reduces the development of precancerous lesions in the mouse colon.

TL;DR: An inter-species chemical signaling system that modulates host immune functions and may play a role in balancing host carriage of commensal and pathogenic C. albicans is revealed.