S
Sarah Hirschberg
Researcher at Ruhr University Bochum
Publications - 6
Citations - 437
Sarah Hirschberg is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Neurodegeneration & Multiple sclerosis. The author has an hindex of 4, co-authored 6 publications receiving 182 citations. Previous affiliations of Sarah Hirschberg include University of Freiburg.
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Journal ArticleDOI
Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism
Alexander Duscha,Barbara Gisevius,Sarah Hirschberg,Nissan Yissachar,Gabriele I. Stangl,Eva Eilers,Eva Eilers,Verian Bader,Stefanie Haase,Johannes Kaisler,Christina David,Ruth Schneider,Riccardo Troisi,Daniel Zent,Tobias Hegelmaier,Nikolaos Dokalis,Sara Gerstein,Sara Del Mare-Roumani,Sivan Amidror,Ori Staszewski,Gereon Poschmann,Kai Stühler,Frank Hirche,András Balogh,Stefan Kempa,Pascal Träger,Mario M. Zaiss,Jacob Bak Holm,Megan G. Massa,Henrik Nielsen,Andreas Faissner,Carsten Lukas,Sören Gatermann,Markus Scholz,Horst Przuntek,Marco Prinz,Sofia K. Forslund,Konstanze F. Winklhofer,Dominik N. Müller,Ralf A. Linker,Ralf Gold,Aiden Haghikia +41 more
TL;DR: It is suggested that PA can serve as a potent immunomodulatory supplement to MS drugs and as an add-on to MS immunotherapy.
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Implications of Diet and The Gut Microbiome in Neuroinflammatory and Neurodegenerative Diseases
TL;DR: The impact of an altered microbiome composition in relation to various diseases is discussed and how the commensal microbiome is shaped is discussed, starting from the beginning of human life.
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Testosterone Differentially Affects T Cells and Neurons in Murine and Human Models of Neuroinflammation and Neurodegeneration.
Megan G. Massa,Christina David,Stefanie Jörg,Johannes Berg,Barbara Gisevius,Sarah Hirschberg,Ralf A. Linker,Ralf Gold,Aiden Haghikia +8 more
TL;DR: Through the alleviation of inflammatory processes and the exacerbation of neurodegenerative processes, androgens may contribute to the epidemiologic sex differentials observed in MS prevalence and course.
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Chitinase 3-like 1 and neurofilament light chain in CSF and CNS atrophy in MS.
Ruth Schneider,Barbara Bellenberg,Barbara Gisevius,Sarah Hirschberg,Roman Sankowski,Marco Prinz,Ralf Gold,Carsten Lukas,Aiden Haghikia +8 more
TL;DR: This study provides Class II evidence that CSF CHI3L1 was associated with spinal cord volume loss and was less affected than NfL by disease duration and age, whereas CSF NFL was associatedWith brain gray matter atrophy.
Journal ArticleDOI
Multiple Sclerosis Patient-Specific Primary Neurons Differentiated from Urinary Renal Epithelial Cells via Induced Pluripotent Stem Cells.
Megan G. Massa,Barbara Gisevius,Sarah Hirschberg,Lisa Hinz,Matthias Schmidt,Ralf Gold,Nora Prochnow,Aiden Haghikia +7 more
TL;DR: The development of such a non-invasive procedure devoid of permanent genetic manipulation during the course of differentiation, in the context of multiple sclerosis, provides an avenue for studies with a greater cell- and human-specific focus, specifically in thecontext of genetic contributions to neurodegeneration and drug discovery.