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Eva Eilers
Researcher at Ruhr University Bochum
Publications - 3
Citations - 301
Eva Eilers is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 1, co-authored 1 publications receiving 120 citations. Previous affiliations of Eva Eilers include Leibniz Institute for Neurobiology.
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Journal ArticleDOI
Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism
Alexander Duscha,Barbara Gisevius,Sarah Hirschberg,Nissan Yissachar,Gabriele I. Stangl,Eva Eilers,Eva Eilers,Verian Bader,Stefanie Haase,Johannes Kaisler,Christina David,Ruth Schneider,Riccardo Troisi,Daniel Zent,Tobias Hegelmaier,Nikolaos Dokalis,Sara Gerstein,Sara Del Mare-Roumani,Sivan Amidror,Ori Staszewski,Gereon Poschmann,Kai Stühler,Frank Hirche,András Balogh,Stefan Kempa,Pascal Träger,Mario M. Zaiss,Jacob Bak Holm,Megan G. Massa,Henrik Nielsen,Andreas Faissner,Carsten Lukas,Sören Gatermann,Markus Scholz,Horst Przuntek,Marco Prinz,Sofia K. Forslund,Konstanze F. Winklhofer,Dominik N. Müller,Ralf A. Linker,Ralf Gold,Aiden Haghikia +41 more
TL;DR: It is suggested that PA can serve as a potent immunomodulatory supplement to MS drugs and as an add-on to MS immunotherapy.
Proceedings ArticleDOI
Identification of multiple sclerosis endophenotypes by high dimensional blood signatures associated with distinct disease trajectories (P1-3.008)
Catharina C. Gross,Andreas Schulte-Mecklenbeck,Olga V. Steinberg,Timo Wirth,Sarah Lauks,Sergio E. Baranzini,Stefan Bittner,Judith Bellmann-Strobl,Eva Eilers,Maria Eveslage,Vinzenz Fleischer,Barbara Gisevius,Sergiu Groppa,Jürgen Haas,Martin Kerschensteiner,Lucienne Kirstein,Catharina Korsukewitz,Lisa Lohmann,J. Lünemann,Felix Lüssi,Gerd Meyer zu Hörste,Jeremias Motte,Tobias Ruck,Nicholas Schwab,Sven G. Meuth,Friedemann Paul,Brigitte C Wildemann,Tania Kümpfel,Ralf Gold,Frauke Zipp,Luisa Klotz,Heinz Wiendl +31 more
TL;DR: Baranzini et al. as discussed by the authors employed high-dimensional flow cytometry and targeted proteomics to identify immune-response signatures in the blood of multiple sclerosis patients predictive for clinical disease trajectories and supporting personalized treatment decisions based on pathobiological principles.
Posted ContentDOI
LUBAC assembles a signaling platform at mitochondria for signal amplification and shuttling of NF-ĸB to the nucleus
Zhixiao Wu,Lena A. Berlemann,Verian Bader,Dominik A. Sehr,Eva Eilers,Alberto Covallero,Jens Meschede,Lena Angersbach,Cathrin Showkat,Jonas B. Michaelis,Christian Münch,Bettina Rieger,Dmitry Namgaladze,M.G. Herrera,Fabienne C. Fiesel,Wolfdieter Springer,Marta Mendes,Jennifer Stepien,Katalin Barkovits,Katrin Marcus,Albert Sickmann,Gunnar Dittmar,Karin B. Busch,Dietmar Riedel,Marisa Brini,Jörg Tatzelt,Tito Calì,Konstanze F. Winklhofer +27 more
TL;DR: It is shown that the NF-ĸB pathway activated by TNF employs mitochondria as a platform for signal amplification and shuttling of activated NF- ĸB to the nucleus, resulting in an increase in mitochondria-nucleus contact sites in a HOIP-dependent manner.