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Seiji Kojima
Researcher at Nagoya University
Publications - 696
Citations - 21007
Seiji Kojima is an academic researcher from Nagoya University. The author has contributed to research in topics: Transplantation & Aplastic anemia. The author has an hindex of 69, co-authored 661 publications receiving 18754 citations. Previous affiliations of Seiji Kojima include Hiroshima University & Fujita Health University.
Papers
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Journal ArticleDOI
Quantitative Analysis of Epstein-Barr Virus Load by Using a Real-Time PCR Assay
Hiroshi Kimura,Makoto Morita,Yumi Yabuta,Kiyotaka Kuzushima,Koji Kato,Seiji Kojima,Takaharu Matsuyama,Tsuneo Morishima +7 more
TL;DR: The results indicate that the real-time PCR assay is useful for diagnosing symptomatic EBV infection and for monitoring the virus load.
Journal ArticleDOI
EBV-associated T/NK–cell lymphoproliferative diseases in nonimmunocompromised hosts: prospective analysis of 108 cases
Hiroshi Kimura,Yoshinori Ito,Shinji Kawabe,Kensei Gotoh,Yoshiyuki Takahashi,Seiji Kojima,Tomoki Naoe,Shinichi Esaki,Atsushi Kikuta,Akihisa Sawada,Keisei Kawa,Koichi Ohshima,Shigeo Nakamura +12 more
TL;DR: Age at onset of disease and liver dysfunction were risk factors for mortality, whereas patients who received transplantation had a better prognosis, and insight into the diagnostic and therapeutic approaches for distinct disease is provided.
Journal ArticleDOI
The landscape of somatic mutations in Down syndrome-related myeloid disorders
Kenichi Yoshida,Tsutomu Toki,Yusuke Okuno,Rika Kanezaki,Yuichi Shiraishi,Aiko Sato-Otsubo,Aiko Sato-Otsubo,Masashi Sanada,Masashi Sanada,Myoung-ja Park,Kiminori Terui,Hiromichi Suzuki,Hiromichi Suzuki,Ayana Kon,Ayana Kon,Yasunobu Nagata,Yasunobu Nagata,Yusuke Sato,Yusuke Sato,Ru Nan Wang,Ru Nan Wang,Norio Shiba,Kenichi Chiba,Hiroko Tanaka,Asahito Hama,Hideki Muramatsu,Daisuke Hasegawa,Kazuhiro Nakamura,Hirokazu Kanegane,Keiko Tsukamoto,Souichi Adachi,Kiyoshi Kawakami,Koji Kato,Ryosei Nishimura,Shai Izraeli,Yasuhide Hayashi,Satoru Miyano,Seiji Kojima,Etsuro Ito,Seishi Ogawa,Seishi Ogawa +40 more
TL;DR: Subsequent AMKL evolves from a pre-existing TAM clone through the acquisition of additional mutations, with major mutational targets including multiple cohesin components and EZH2, KANSL1 and other epigenetic regulators, as well as common signaling pathways, such as the JAK family kinases, MPL, SH2B3 and multiple RAS pathway genes.
Book ChapterDOI
Flagellar motility in bacteria structure and function of flagellar motor.
TL;DR: This chapter surveys the current knowledge of the flagellar system, based mostly on studies from Salmonella, E. coli, and marine species Vibrio alginolyticus, supplemented with distinct aspects of other bacterial species revealed by recent studies.
Journal ArticleDOI
The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease
Christian P. Kratz,Charlotte M. Niemeyer,Robert P. Castleberry,Mualla Cetin,Eva Bergsträsser,Peter D. Emanuel,Henrik Hasle,Gabriela Kardos,Cornelia Klein,Seiji Kojima,Jan Stary,M. Trebo,Marco Zecca,Bruce D. Gelb,Marco Tartaglia,Mignon L. Loh +15 more
TL;DR: There is a genotype/phenotype correlation in the spectrum of PTPN11 mutations found in patients with JMML, NS/MPD, and NS, which supports the need to characterize the range of hematologic abnormalities in individuals with NS and to better define the impact of the PTPn11 lesion on the disease course.