S
Seog K. Kim
Researcher at Yeungnam University
Publications - 162
Citations - 6025
Seog K. Kim is an academic researcher from Yeungnam University. The author has contributed to research in topics: Circular dichroism & Linear dichroism. The author has an hindex of 29, co-authored 162 publications receiving 5698 citations. Previous affiliations of Seog K. Kim include New York University & Pohang University of Science and Technology.
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Rotation of periphery methylpyridine of meso-tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2, 3, 4) and its selective binding to native and synthetic DNAs.
TL;DR: The binding mode of meso-tetrakis(n-N-methylpyridiniumyl)porphyrin to various DNAs was studied and close analysis of the spectral properties led to conclude that o-TMPyP sits in the major groove.
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Binding mode of porphyrins to poly[d(A-T)(2)] and poly[d(G-C)(2)].
TL;DR: Close analysis of the linear dichroism result reveals that all porphyrins exhibit outside binding when complexed with poly[d(A-T)(2)], regardless of the existence of a central metal and side chain, and demonstrates that an energy transfer from the excited nucleo-bases to porphyrs can occur for metalloporphyrin.
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Simultaneous Binding of Ruthenium(II) [(1,10-Phenanthroline)2dipyridophenazine]2+ and Minor Groove Binder 4‘,6-Diamidino-2-phenylindole to Poly[d(A−T)2] at High Binding Densities: Observation of Fluorescence Resonance Energy Trasfer Across the DNA Stem
TL;DR: In this paper, the photophysical properties of Δ- and Λ-[Ru(phenanthroline)2dipyrido[3,2-a:2‘,3‘-c]phenazine]2+ ([Ru (phen)2DPPZ]2+) bound to poly[d(A−T)2] in the presence and absence of 4',6-diamidino-2-phenylindole...
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Mechanisms of Oxidation of Guanine in DNA by Carbonate Radical Anion, a Decomposition Product of Nitrosoperoxycarbonate
Young-Ae Lee,Byeong Hwa Yun,Seog K. Kim,Yelena Margolin,Peter C. Dedon,Nicholas E. Geacintov,Vladimir Shafirovich +6 more
TL;DR: The lack of dependence of k(5) on sequence context indicates that the one-electron oxidation of guanine in DNA by CO(3) (.-) radicals occurs by an inner-sphere mechanism.
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Influence of carboxylic acid functionalities in ruthenium (II) polypyridyl complexes on DNA binding, cytotoxicity and antioxidant activity: Synthesis, structure and in vitro anticancer activity
Thangavel Sathiya Kamatchi,Nataraj Chitrapriya,Seog K. Kim,Frank R. Fronczek,Karuppannan Natarajan +4 more
TL;DR: Inclusion of COOH caused significant differences in DNA binding, cytotoxicity and antioxidant activity, and validated against a panel of cancer cell lines and free radicals showed that 3 and 4 possess quite high anticancer and antioxidant activities over 1, 2 and standard drugs.