S
Serge Pérez
Researcher at University of Grenoble
Publications - 229
Citations - 13585
Serge Pérez is an academic researcher from University of Grenoble. The author has contributed to research in topics: Crystal structure & Conformational isomerism. The author has an hindex of 57, co-authored 224 publications receiving 12411 citations. Previous affiliations of Serge Pérez include Université de Montréal & European Synchrotron Radiation Facility.
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Molecular modelling of the interaction between the catalytic site of pig pancreatic alpha-amylase and amylose fragments.
TL;DR: A stereo chemical refinement of the crystalline complex between porcine pancreatic alpha-amylase and a pseudopentasaccharide from the amylostatin family has been performed through molecular mechanics calculations, providing a starting point for docking a maltopentaose moiety within the catalytic site, in the absence of water.
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Crystal Structure of Tricolorin A: Molecular Rationale for the Biological Properties of Resin Glycosides Found in Some Mexican Herbal Remedies
Anna Rencurosi,Edward P. Mitchell,Gianluca Cioci,Serge Pérez,Rogelio Pereda-Miranda,Anne Imberty +5 more
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A pipeline to translate glycosaminoglycan sequences into 3D models. Application to the exploration of glycosaminoglycan conformational space
Olivier Clerc,Julien Mariethoz,Alain Rivet,Frédérique Lisacek,Frédérique Lisacek,Serge Pérez,Sylvie Ricard-Blum +6 more
TL;DR: The building of an automated pipeline to standardize the format of GAG sequences interacting with proteins manually curated from the literature is reported, and a converter to automatically translate the GlycoCT code of a GAG sequence into the input file required to construct a three-dimensional model is developed.
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Negatively charged glyconanoparticles modulate and stabilize the secondary structures of a gp120 V3 loop peptide: toward fully synthetic HIV vaccine candidates.
Paolo Di Gianvincenzo,Javier Ezquerra Calvo,Serge Pérez,Amparo Álvarez,Luis M. Bedoya,Luis M. Bedoya,José Alcamí,Soledad Penadés +7 more
TL;DR: Modulation and stabilization of either the α-helix or β-strand conformation of the V3 peptide by conjugation to negatively charged gold glyconanoparticles (GNPs) open up the way for the design of new fully synthetic HIV vaccine candidates.
Journal ArticleDOI
Assessing Sucrose Hydroxyl Acidities Through Semiempirical Calculations
Stephan Houdier,Serge Pérez +1 more
TL;DR: In this article, the chemical reactivity of sucrose has been evaluated using semiempirical molecular orbital (AM1 and PM3) frameworks, and a simple conformational equilibrium consistent with NMR experiments was taken into account.