S
Serge Pérez
Researcher at University of Grenoble
Publications - 229
Citations - 13585
Serge Pérez is an academic researcher from University of Grenoble. The author has contributed to research in topics: Crystal structure & Conformational isomerism. The author has an hindex of 57, co-authored 224 publications receiving 12411 citations. Previous affiliations of Serge Pérez include Université de Montréal & European Synchrotron Radiation Facility.
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Unraveling the complex enzymatic machinery making a key galactolipid in chloroplast membrane: a multiscale computer simulation
TL;DR: The intricacy of the organization and the process of active complex assembly and synthesis have been investigated at the Coarse-Grained and All-Atom of computer simulation levels to cover large spatial and temporal scales.
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Low-temperature neutron diffraction structures of N-glycoprotein linkage models and analogues: structure refinement and trifurcated hydrogen bonds.
Gianluca Cioci,Amrita Srivastava,Duraikkannu Loganathan,Sax A. Mason,Serge Pérez,Anne Imberty +5 more
TL;DR: These first crystal structures of N-acetylated carbohydrates obtained by neutron diffraction provide high-resolution geometrical parameters that can be used for force-field parametrization and subsequent molecular dynamics simulation ofN-glycoproteins.
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A structural study of 2-O-lauroylsucrose with molecular modeling and NMR methods
TL;DR: In this paper, the preferred conformations of sucrose, 2-O -acetylsucrose and 2- O -lauroyl sucrose have been explored with the MM3 force field.
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Single-coordinate-driving method for molecular docking: Application to modeling of guest inclusion in cyclodextrin
TL;DR: The philosophy of the newly developed approach is not only to find the best dock for the receptor-ligand(s) system, but also to describe all the important binding modes and provide a good starting point for studying the dynamics within the cavity during the docking process.
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Conformational features of C-glycosyl compounds: crystal structure and molecular modelling of "methyl C-gentiobioside".
Alain Neuman,Francois Longchambon,Oukacha Abbes,H. Gillier-Pandraud,Serge Pérez,Dominique Rouzaud,Pierre Sinaÿ +6 more
TL;DR: This crystal structure is the first experimental characterization of a "C-disaccharide", which has a restricted flexibility and each of the low-energy conformers in vacuo has a value of phi centered about 60 degrees, in agreement with the solid state conformation.