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Serge Pérez

Researcher at University of Grenoble

Publications -  229
Citations -  13585

Serge Pérez is an academic researcher from University of Grenoble. The author has contributed to research in topics: Crystal structure & Conformational isomerism. The author has an hindex of 57, co-authored 224 publications receiving 12411 citations. Previous affiliations of Serge Pérez include Université de Montréal & European Synchrotron Radiation Facility.

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Theoretical aspects of oligosaccharide conformation

TL;DR: A review of recent advances in the field of theoretical investigations of oligosaccharides, including glycolipids, can be found in this article, where a number of theoretical approaches have been developed to deal with the complications arising from such features.
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Combined NMR and molecular modeling study of an iduronic acid-containing trisaccharide related to antithrombotic heparin fragments.

TL;DR: Results are in keeping with the observation that 2-O-sulfated pentasaccharides display a similar affinity for antithrombin III as their 2-N-Sulfated counterparts.
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Structure and dynamics of the conserved protein GPI anchor core inserted into detergent micelles.

TL;DR: The pseudopentasaccharide structure, which was not affected by incorporation of (1) into the micelle, showed a complex dynamic behaviour with a faster relative motion at the terminal mannopyranose unit and decreased mobility close to themicelle.
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Insights on the conformational properties of hyaluronic acid by using NMR residual dipolar couplings and MD simulations

TL;DR: The approach consisted in the measurements of NMR residual dipolar coupling (RDC) which were used to filter the molecular dynamics data by retaining those structures which were in agreement with the experimental observations, which permitted the assessment that hyaluronic acid can adopt two different arrangements.