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Şevki Adem
Researcher at Çankırı Karatekin University
Publications - 54
Citations - 796
Şevki Adem is an academic researcher from Çankırı Karatekin University. The author has contributed to research in topics: Enzyme & Chemistry. The author has an hindex of 11, co-authored 40 publications receiving 391 citations.
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Identification of Potent COVID-19 Main Protease (Mpro) Inhibitors from Natural Polyphenols: An in Silico Strategy Unveils a Hope against CORONA
TL;DR: Wang et al. as mentioned in this paper evaluated the efficacy of medicinal plant-based bioactive compounds against SARS-CoV-2 Mpro by molecular docking study using Molegro Virtual Docker 7 to analyze the inhibition probability of these compounds against COVID-19.
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Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19.
Şevki Adem,Volkan Eyupoglu,Iqra Sarfraz,Azhar Rasul,Ameer Fawad Zahoor,Muhammad Ali,Mohnad Abdalla,Ibrahim M. Ibrahim,Abdo A. Elfiky +8 more
TL;DR: This study will hopefully pave a way for development of phytonutrients-based antiviral therapeutic for treatment or prevention of COVID-19 and further studies are recommended to evaluate the antiviral effects of these phytochemicals against SARS-CoV-2 in in vitro and in vivo models.
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Synthesis, spectroscopic characterizations, enzyme inhibition, molecular docking study and DFT calculations of new Schiff bases of sulfa drugs
TL;DR: In this paper, new Schiff bases were synthesized (Z)-4-((4-(diethylamino)benzylidene)amino)-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide (L1) and (Z]-4-(4-(dimethylamino), amino amino) amino)-n-(5-methylisoxosol-3-yl), N-(5 -methylisocazol)-3 -yl)benedienesulfoneamide (
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Ginkgetin: A natural biflavone with versatile pharmacological activities.
Muhammad Adnan,Azhar Rasul,Ghulam Hussain,Muhammad Ajmal Shah,Muhammad Kashif Zahoor,Haseeb Anwar,Iqra Sarfraz,Ammara Riaz,Maleeha Manzoor,Şevki Adem,Zeliha Selamoglu +10 more
TL;DR: Ginkgetin shows substantial preventive or therapeutic effects in in vivo models of many diseases including atherosclerosis, cancer, neurodegenerative, hepatic, influenza, and inflammatory diseases.
Journal ArticleDOI
Hispolon: A natural polyphenol and emerging cancer killer by multiple cellular signaling pathways.
Ayesha Sarfraz,Azhar Rasul,Iqra Sarfraz,Muhammad Ajmal Shah,Ghulam Hussain,Nusrat Shafiq,Muqaddas Masood,Şevki Adem,Satyajit D. Sarker,Xiaomeng Li +9 more
TL;DR: It is proposed that hispolon provides a novel opportunity for pharmacological applications and its styrylpyrone carbon skeleton might serve as an attractive scaffold for drug development, and future researchers are recommended to assess bioavailability, toxicological limits, pharmacokinetic and pharmacodynamic profiles of hisPolon, in order to establish its potential as a potent multi-targeted drug in the near future.