Seyed Javad Mowla

TL;DR: The biosynthesis and post-translational processing of the brain-derived neurotrophic factor precursor (pro-BDNF) in cells infected with a pro-BD NF-encoding vaccinia virus is examined to suggest that 28-kDa pro- BDNF is not an obligatory intermediate in the formation of the 14-k da form in the constitutive secretory pathway.

TL;DR: In vitro studies suggest that SKI-1 is a Ca2+-dependent serine proteinase exhibiting a wide pH optimum for cleavage of pro-brain-derived neurotrophic factor and phylogenetically ancestral human, rat, and mouse type I membrane-bound proteinase called subtilisin/kexin-isozyme-1 (SKI- 1).

TL;DR: A distinctive expression pattern for OCT4 spliced variants in different cell types is demonstrated and the necessity of defining the type of OCT4 when addressing the expression of this gene in different human cells is highlighted.

TL;DR: This study demonstrated, for the first time, the expression of OCT‐4 in bladder cancer and a further clue to the involvement of embryonic genes in carcinogenesis.

TL;DR: The findings suggest that exosomal transfer of miR-100 may be a novel mechanism underlying the paracrine effects of MSC-derived exosomes and may provide a means by which these vesicles can modulate vascular responses within the microenvironment of breast cancer cells.