S
Sharmila Majumdar
Researcher at University of California, San Francisco
Publications - 505
Citations - 29773
Sharmila Majumdar is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Osteoarthritis & Cartilage. The author has an hindex of 88, co-authored 477 publications receiving 27074 citations. Previous affiliations of Sharmila Majumdar include University of California & Georgia Regents University.
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Journal ArticleDOI
Changes in bone structure and mass with advancing age in the male C57BL/6J mouse.
Bernard P. Halloran,Virginia L. Ferguson,Steven J. Simske,Andrew J. Burghardt,Laura L. Venton,Sharmila Majumdar +5 more
TL;DR: The rapid early loss of cancellous bone suggests that bone loss is not just associated with old age in the mouse but rather occurs as a continuum from early growth, and the C57BL/6J male mouse maybe a useful model to study at least some aspects of age‐related bone loss in humans.
Journal ArticleDOI
Microarchitectural deterioration of cortical and trabecular bone: differing effects of denosumab and alendronate.
Ego Seeman,Pierre D. Delmas,David A. Hanley,Deborah E. Sellmeyer,Angela M. Cheung,Elizabeth Shane,Ann E. Kearns,Thierry Thomas,Steven K. Boyd,Stephanie Boutroy,Cesar E. Bogado,Sharmila Majumdar,Michelle Fan,Cesar Libanati,Jose R. Zanchetta +14 more
TL;DR: The data suggest that structural decay owing to bone remodeling and progression of bone fragility may be prevented more effectively with denosumab.
Journal ArticleDOI
High-resolution Computed Tomography for Clinical Imaging of Bone Microarchitecture
TL;DR: CT currently provides quantitative measures of bone structure and may be used for estimating bone strength mathematically and the techniques may provide clinically relevant information by enhancing the understanding of fracture risk and establishing the efficacy of antifracture for osteoporosis and other bone metabolic disorders.
Journal ArticleDOI
Osteoarthritis of the knee: comparison of radiography, CT, and MR imaging to assess extent and severity.
Wing P. Chan,Peter Lang,M. P. Stevens,K Sack,Sharmila Majumdar,D. W. Stoller,C. Basch,Harry K. Genant +7 more
TL;DR: MR is more sensitive than radiography and CT for assessing the extent and severity of osteoarthritic changes and frequently shows tricompartmental disease in patients in whom radiographyand CT show only bicompartmentsal involvement.
Journal ArticleDOI
Insulin‐Like Growth Factor I Is Required for the Anabolic Actions of Parathyroid Hormone on Mouse Bone
Daniel D. Bikle,Takeshi Sakata,Colin Leary,Hashem Z Elalieh,David G. Ginzinger,Clifford J. Rosen,Wesley G. Beamer,Sharmila Majumdar,Bernard P. Halloran +8 more
TL;DR: The results indicate that IGF‐I is required for the anabolic actions of PTH on bone formation, but the defect lies distal to the initial response of the osteoblast to PTH.