S
Sharon Jenkins
Researcher at Moorfields Eye Hospital
Publications - 39
Citations - 2986
Sharon Jenkins is an academic researcher from Moorfields Eye Hospital. The author has contributed to research in topics: Retinitis pigmentosa & Gene mutation. The author has an hindex of 27, co-authored 39 publications receiving 2645 citations. Previous affiliations of Sharon Jenkins include University College London & St Bartholomew's Hospital.
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Journal ArticleDOI
Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation Carriers A European Cohort Study
Ingrid A.W. van Rijsingen,Eloisa Arbustini,Perry M. Elliott,J Mogensen,Johanna F. Hermans-van Ast,Anneke J. van der Kooi,J. Peter van Tintelen,Maarten P. van den Berg,Andrea Pilotto,Michele Pasotti,Sharon Jenkins,Camilla Rowland,Uzma Aslam,Arthur A.M. Wilde,Andreas Perrot,Sabine Pankuweit,Aeilko H. Zwinderman,Philippe Charron,Yigal M. Pinto +18 more
TL;DR: In this paper, risk factors that predict malignant ventricular arrhythmias (MVA) in Lamin A/C (LMNA) mutation carriers were determined, defined as sudden cardiac death, resuscitation and appropriate implantable cardioverter-defibrillator (ICD) treatment.
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Mutations in the Lamin A/C gene mimic arrhythmogenic right ventricular cardiomyopathy
Giovanni Quarta,Petros Syrris,Michael Ashworth,Sharon Jenkins,Krisztina Zuborne Alapi,John M. Morgan,Alison Muir,Antonios Pantazis,William J. McKenna,Perry M. Elliott,Perry M. Elliott +10 more
TL;DR: Lamin A/C gene should be added to desmosomal genes when genetically testing patients with suspected ARVC, particularly when they also have ECG evidence for conduction disease.
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Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing
Luis R. Lopes,Anna Zekavati,Petros Syrris,Mike Hubank,Claudia Giambartolomei,Chrysoula Dalageorgou,Sharon Jenkins,William J. McKenna,Vincent Plagnol,Perry M. Elliott +9 more
TL;DR: This study provides the first large-scale quantitative analysis of the prevalence of sarcomere protein gene variants in patients with HCM using HTS technology.
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Prevalence of sarcomere protein gene mutations in preadolescent children with hypertrophic cardiomyopathy.
Juan Pablo Kaski,Petros Syrris,Maria Teresa Tome Esteban,Sharon Jenkins,Antonios Pantazis,John E. Deanfield,William J. McKenna,Perry M. Elliott +7 more
TL;DR: Familial disease is common among infants and children with HCM and that, in most cases, disease is caused by mutations in cardiac sarcomere protein genes, the major implication is that all first-degree relatives of any child diagnosed with H CM should be offered screening.
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Functional characterisation and serial imaging of abnormal fundus autofluorescence in patients with retinitis pigmentosa and normal visual acuity
Anthony G. Robson,Zubin Saihan,Sharon Jenkins,Fred W. Fitzke,A C Bird,Andrew R. Webster,G E Holder +6 more
TL;DR: High density rings of AF, seen in some patients with RP with good visual acuity, demarcate areas of preserved central photopic function, which can show progressive constriction accompanied by increasing macular dysfunction.