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Luis R. Lopes

Researcher at St Bartholomew's Hospital

Publications -  126
Citations -  3468

Luis R. Lopes is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Hypertrophic cardiomyopathy & Medicine. The author has an hindex of 20, co-authored 114 publications receiving 2636 citations. Previous affiliations of Luis R. Lopes include Barts Health NHS Trust & University College Hospital.

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The UK10K project identifies rare variants in health and disease

Klaudia Walter, +241 more
TL;DR: The contribution of rare and low-frequency variants to human traits is largely unexplored as mentioned in this paper, but the contribution of these variants to the human traits has not yet been fully explored.
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Atlas of the clinical genetics of human dilated cardiomyopathy

Jan Haas, +60 more
- 07 May 2015 - 
TL;DR: This is to the authors' knowledge, the first study that comprehensively investigated the genetics of DCM in a large-scale cohort and across a broad gene panel of the known DCM genes and underline the high analytical quality and feasibility of Next-Generation Sequencing in clinical genetic diagnostics.
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Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing

Luis R. Lopes, +9 more
- 01 Apr 2013 - 
TL;DR: This study provides the first large-scale quantitative analysis of the prevalence of sarcomere protein gene variants in patients with HCM using HTS technology.
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Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Andrea Rodriguez-Martinez, +1361 more
- 07 Nov 2020 - 
TL;DR: Girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries and boys in central and western Europe had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI.
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A systematic review and meta-analysis of genotype–phenotype associations in patients with hypertrophic cardiomyopathy caused by sarcomeric protein mutations

Luis R. Lopes, +2 more
- 15 Dec 2013 - 
TL;DR: The presence of a mutation in any sarcomere gene is associated with a number of clinical features and the heterogeneous nature of the disease and the inconsistency of study design precludes the establishment of more precise genotype–phenotype relationships.