S
Sharon Kean
Researcher at Robertson Centre for Biostatistics
Publications - 31
Citations - 4995
Sharon Kean is an academic researcher from Robertson Centre for Biostatistics. The author has contributed to research in topics: Randomized controlled trial & Population. The author has an hindex of 16, co-authored 28 publications receiving 3735 citations. Previous affiliations of Sharon Kean include University of Glasgow.
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Journal ArticleDOI
Xanthine oxidase inhibition for the improvement of long-term outcomes following ischaemic stroke and transient ischaemic attack (XILO-FIST) - Protocol for a randomised double blind placebo-controlled clinical trial.
Jesse Dawson,Niall M. Broomfield,Krishna A Dani,David Alexander Dickie,Alex S. F. Doney,Kirsten P. Forbes,Graeme Houston,Sharon Kean,Kennedy R. Lees,Alex McConnachie,Keith W. Muir,Terry J Quinn,Allan D. Struthers,Matthew Walters +13 more
TL;DR: If white matter hyperintensity progression is reduced, allopurinol could be an effective preventative treatment for patients with ischaemic stroke and clinical endpoint studies would be needed.
Journal ArticleDOI
Randomized Trial—PrEscription of intraDialytic exercise to improve quAlity of Life in Patients Receiving Hemodialysis
Sharlene A. Greenwood,Sharlene A. Greenwood,Pelagia Koufaki,Jamie H. Macdonald,Sunil Bhandari,James O. Burton,Indranil Dasgupta,Ken Farrington,Ian Ford,Philip A. Kalra,Sharon Kean,Mick Kumwenda,Iain C. Macdougall,Iain C. Macdougall,Claudia-Martina Messow,Sandip Mitra,Chante Reid,Alice C. Smith,Maarten W. Taal,Peter C. Thomson,David C. Wheeler,David C. Wheeler,Claire White,Magdi Yaqoob,Thomas H. Mercer +24 more
TL;DR: A 6-month intradialytic aerobic exercise program was not clinically beneficial in improving HRQoL as delivered to this cohort of deconditioned patients on HD.
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Erratum: Correction: The effect of a programme to improve men's sedentary time and physical activity: The European Fans in Training (EuroFIT) randomised controlled trial (PLoS medicine (2019) 16 2 (e1002736))
Sally Wyke,Christopher Bunn,Eivind Andersen,Marlene N. Silva,Femke van Nassau,Paula McSkimming,Spyros Kolovos,Jason M.R. Gill,Cindy M. Gray,Kate Hunt,Annie S. Anderson,Judith E. Bosmans,Judith G. M. Jelsma,Sharon Kean,Nicolas Lemyre,David W. Loudon,Lisa Macaulay,Douglas J. Maxwell,Alex McConnachie,Nanette Mutrie,Maria Nijhuis van der Sanden,Hugo V. Pereira,Matthew Philpott,Glyn C. Roberts,John Rooksby,Øystein B. Røynesdal,Naveed Sattar,Marit Sørensen,Pedro J. Teixeira,Shaun Treweek,Theo van Achterberg,Irene van de Glind,Willem van Mechelen,Hidde P. van der Ploeg +33 more
TL;DR: This research presents a novel probabilistic approach to estimating the response of the immune system to laser-spot assisted, 3D image recognition technology.
Journal ArticleDOI
The PrEscription of intraDialytic exercise to improve quAlity of Life in patients with chronic kidney disease trial: study design and baseline data for a multicentre randomized controlled trial.
Sharlene A. Greenwood,Sharlene A. Greenwood,Pelagia Koufaki,Jamie H. Macdonald,Sunil Bhandari,James O. Burton,Indranil Dasgupta,Ken Farrington,Ian Ford,Philip A. Kalra,Sharon Kean,Mick Kumwenda,Iain C. Macdougall,Iain C. Macdougall,Claudia-Martina Messow,Sandip Mitra,Chante Reid,Alice C. Smith,Maarten W. Taal,Peter C. Thomson,David C. Wheeler,David C. Wheeler,Claire White,Magdi Yaqoob,Thomas H. Mercer +24 more
TL;DR: The results from this study will address a significant knowledge gap in the prescription of exercise interventions for patients receiving maintenance HD therapy and inform the development of intradialytic exercise programmes both nationally and internationally.
Journal ArticleDOI
Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over.
R. S. du Puy,Iris Postmus,David J. Stott,Manuel R. Blum,Rosalinde K. E. Poortvliet,W.P.J. den Elzen,Robin P. Peeters,B. C. van Munster,Bruce H. R. Wolffenbuttel,Rudi G. J. Westendorp,Patricia M. Kearney,Ian Ford,Sharon Kean,Claudia-Martina Messow,Torquil Watt,Joop Jukema,Olaf M. Dekkers,Johannes W. A. Smit,Nicolas Rodondi,Jacobijn Gussekloo,Simon P. Mooijaart +20 more
TL;DR: The combined analysis of participants in the IEMO 80-plus thyroid trial with the participants aged over 80 in the TRUST trial will provide the largest experimental evidence base on multimodal effects of levothyroxine treatment in 80- plus persons to date.