S
Sheri K. Wilcox
Researcher at Scripps Research Institute
Publications - 47
Citations - 4291
Sheri K. Wilcox is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Aptamer & Systematic evolution of ligands by exponential enrichment. The author has an hindex of 20, co-authored 46 publications receiving 3383 citations. Previous affiliations of Sheri K. Wilcox include University of Colorado Boulder & Pearson Education.
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Journal ArticleDOI
Aptamer-based multiplexed proteomic technology for biomarker discovery
Larry Gold,Deborah Ayers,Jennifer Bertino,Christopher Bock,Ashley Bock,Edward N. Brody,Jeffrey D. Carter,Andrew B. Dalby,Bruce E. Eaton,Tim Fitzwater,Dylan Flather,Ashley Forbes,Trudi Foreman,Cate Fowler,Bharat Gawande,Meredith Goss,Magda Gunn,Shashi Kumar Gupta,Dennis Halladay,Jim Heil,Joe Heilig,Brian Hicke,Gregory M. Husar,Nebojsa Janjic,Thale C. Jarvis,Susan Jennings,Evaldas Katilius,Tracy R. Keeney,Nancy Kim,Tad H. Koch,Stephan Kraemer,Luke Kroiss,Ngan Le,Daniel M. Levine,Wes Lindsey,Bridget Lollo,Wes Mayfield,Mike Mehan,Robert Mehler,Sally K. Nelson,Michele Nelson,Dan Nieuwlandt,Malti Nikrad,Urs A. Ochsner,Rachel Ostroff,Matt Otis,Thomas S. Parker,Steve Pietrasiewicz,Daniel I. Resnicow,John C. Rohloff,Glenn Sanders,Sarah Sattin,Daniel Schneider,Britta Singer,Martin Stanton,Alana Sterkel,Alex Stewart,Suzanne Stratford,Jonathan D. Vaught,Mike Vrkljan,Jeffrey J. Walker,Mike Watrobka,Sheela Waugh,Allison Weiss,Sheri K. Wilcox,Alexey D. Wolfson,Steven K. Wolk,Chi Zhang,Dom Zichi +68 more
TL;DR: A versatile and powerful tool that allows large-scale comparison of proteome profiles among discrete populations, which will enable the discovery of novel biomarkers in a manner that is unencumbered by the incomplete knowledge of biology, thereby helping to advance the next generation of evidence-based medicine.
Journal ArticleDOI
Genomic atlas of the human plasma proteome.
Benjamin B. Sun,Joseph C. Maranville,James E. Peters,James E. Peters,David Stacey,James R Staley,James A. Blackshaw,Stephen Burgess,Tao Jiang,Ellie Paige,Ellie Paige,Praveen Surendran,Clare Oliver-Williams,Mihir A Kamat,Bram P. Prins,Sheri K. Wilcox,Erik S Zimmerman,An Chi,Narinder Bansal,Narinder Bansal,Sarah L. Spain,Angela M. Wood,Nicholas W. Morrell,Nicholas W. Morrell,John Bradley,Nebojsa Janjic,David J. Roberts,David J. Roberts,Willem H. Ouwehand,John A. Todd,Nicole Soranzo,Karsten Suhre,Dirk S. Paul,Caroline S. Fox,Robert M. Plenge,John Danesh,John Danesh,Heiko Runz,Adam S. Butterworth +38 more
TL;DR: The genetic architecture of the human plasma proteome in healthy blood donors from the INTERVAL study is characterized, and it is shown that protein quantitative trait loci overlap with gene expression quantitative traits, as well as with disease-associated loci, and evidence that protein biomarkers have causal roles in disease is found.
Journal ArticleDOI
Aptamer-based multiplexed proteomic technology for biomarker discovery
Larry Gold,Deborah Ayers,Jennifer Bertino,Christopher Bock,Ashley Bock,Edward N. Brody,Jeffrey D. Carter,Virginia Cunningham,Andrew B. Dalby,Bruce E. Eaton,Tim Fitzwater,Dylan Flather,Ashley Forbes,Trudi Foreman,Cate Fowler,Bharat Gawande,Meredith Goss,Magda Gunn,Shashi Kumar Gupta,Dennis Halladay,Jim Heil,Joe Heilig,Brian Hicke,Gregory M. Husar,Nebojsa Janjic,Thale C. Jarvis,Susan Jennings,Evaldas Katilius,Tracy R. Keeney,Nancy Kim,Terese Kaske,Tad H. Koch,Stephan Kraemer,Luke Kroiss,Ngan Le,Daniel M. Levine,Wes Lindsey,Bridget Lollo,Wes Mayfield,Mike Mehan,Robert Mehler,Michele Nelson,Sally K. Nelson,Dan Nieuwlandt,Malti Nikrad,Urs A. Ochsner,Rachel Ostroff,Matt Otis,Thomas S. Parker,Steve Pietrasiewicz,Daniel I. Resnicow,John C. Rohloff,Glenn Sanders,Sarah Sattin,Daniel Schneider,Britta Singer,Martin Stanton,Alana Sterkel,Alex Stewart,Suzanne Stratford,Jonathan D. Vaught,Mike Vrkljan,Jeffrey J. Walker,Mike Watrobka,Sheela Waugh,Allison Weiss,Sheri K. Wilcox,Alexey D. Wolfson,Steve Wolk,Chi Zhang,Dom Zichi +70 more
TL;DR: A versatile and powerful tool that allows large-scale comparison of proteome profiles among discrete populations and will enable the discovery of novel biomarkers in a manner that is unencumbered by the incomplete knowledge of biology, thereby helping to advance the next generation of evidence-based medicine.
Journal ArticleDOI
Expanding the Chemistry of DNA for in Vitro Selection
Jonathan D. Vaught,Chris Bock,Jeffrey D. Carter,Tim Fitzwater,Matt Otis,Daniel J. Schneider,Justin C. Rolando,Sheela Waugh,Sheri K. Wilcox,Bruce E. Eaton +9 more
TL;DR: Six new 5-position modified dUTP derivatives connected by a unique amide linkage were synthesized and tested for compatibility with the enzymatic steps of in vitro selection, resulting in the first successful isolation of DNA aptamers able to bind TNFRSF9 with high affinity.
Journal ArticleDOI
From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay.
Stephan Kraemer,Jonathan D. Vaught,Christopher Bock,Larry Gold,Evaldas Katilius,Tracy R. Keeney,Nancy Kim,Nicholas A. Saccomano,Sheri K. Wilcox,Dom Zichi,Glenn Sanders +10 more
TL;DR: It is demonstrated that quantification by microarray-based hybridization, Luminex bead-based methods, and qPCR are each compatible with the SOMAmer platform, further expanding the breadth of proteomic applications for a wide user community.