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Shinichi Tsutsumi
Researcher at Gunma University
Publications - 16
Citations - 1075
Shinichi Tsutsumi is an academic researcher from Gunma University. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell transplantation for articular cartilage repair. The author has an hindex of 11, co-authored 15 publications receiving 1050 citations. Previous affiliations of Shinichi Tsutsumi include Hiroshima University.
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Journal ArticleDOI
Retention of Multilineage Differentiation Potential of Mesenchymal Cells during Proliferation in Response to FGF
Shinichi Tsutsumi,Atsushi Shimazu,Kazuko Miyazaki,Haiou Pan,Chika Koike,Eri Yoshida,Kenji Takagishi,Yukio Kato +7 more
TL;DR: It is suggested that FGFs play a crucial role in self-renewal of MSC, and all MSC expanded in vitro with FGF-2, but not without FGF, differentiated to chondrocytes in pellet cultures.
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A new technique to expand human mesenchymal stem cells using basement membrane extracellular matrix.
Takehiro Matsubara,Shinichi Tsutsumi,Haiou Pan,Hisatada Hiraoka,Ryo Oda,Masahiro Nishimura,Hiroshi Kawaguchi,Kouzou Nakamura,Yukio Kato +8 more
TL;DR: The growth rate and the proliferative life span of the stem cells markedly increased using tissue culture dishes coated with a basement membrane-like extracellular matrix, which was produced by PYS-2 cells or primary endothelial cells.
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Evaluation of posterolateral spinal fusion using mesenchymal stem cells: differences with or without osteogenic differentiation.
TL;DR: The present study suggested that MSCs that have been cultured with osteogenic differentiation medium may induce the formation of new bone in experimental spinal fusion.
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Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP.
Mitsuhide Noshiro,Takeshi Kawamoto,Masae Furukawa,Katsumi Fujimoto,Yuzo Yoshida,Eri Sasabe,Shinichi Tsutsumi,Taizo Hamada,Sato Honma,Ken-ichi Honma,Yukio Kato +10 more
TL;DR: DEC2, but not DEC1, works as a direct output mediator that transmits the circadian signals to the hepatic functions, including the CYP7A, CYP8B, and CYP51 expression.
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Transplantation of autologous rabbit BM-derived mesenchymal stromal cells embedded in hyaluronic acid gel sponge into osteochondral defects of the knee
TL;DR: Data suggest that the autologous transplantation of MSC embedded in hyaluronan-based material may support chondrogenic differentiation and be useful for osteochondral defect repair.