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Shuji Oh-ishi
Researcher at Tokyo Medical University
Publications - 90
Citations - 2664
Shuji Oh-ishi is an academic researcher from Tokyo Medical University. The author has contributed to research in topics: Brown adipose tissue & Superoxide dismutase. The author has an hindex of 26, co-authored 87 publications receiving 2544 citations. Previous affiliations of Shuji Oh-ishi include Washington University in St. Louis & National Defense Medical College.
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Journal ArticleDOI
Reactive Nitrogen Intermediates Promote Low Density Lipoprotein Oxidation in Human Atherosclerotic Intima
Christiaan Leeuwenburgh,Medora M. Hardy,Stanley L. Hazen,Peter Wagner,Shuji Oh-ishi,Urs P. Steinbrecher,Jay W. Heinecke +6 more
TL;DR: The detection of 3-nitrotyrosine in LDL isolated from vascular lesions raises the possibility that NO, by virtue of its ability to form reactive nitrogen intermediates, may promote atherogenesis, counteracting the well-established anti-atherogenic effects of NO.
Journal ArticleDOI
Strenuous endurance training in humans reduces oxidative stress following exhausting exercise.
Hiromi Miyazaki,Shuji Oh-ishi,Takako Ookawara,Takako Kizaki,Koji Toshinai,Sung Ha,Shukoh Haga,Li Li Ji,Hideki Ohno +8 more
TL;DR: It is indicated that high-intensity endurance training can elevate antioxidant enzyme activities in erythrocytes, and decrease neutrophil O2•− production in response to exhausting exercise, and this up-regulation in antioxidant defences was accompanied by a reduction in exercise-induced lipid peroxidation in ERYthrocyte membrane.
Journal ArticleDOI
Tissue distribution of immunoreactive mouse extracellular superoxide dismutase
Tomomi Ookawara,Nobuo Imazeki,Osamu Matsubara,Takako Kizaki,Shuji Oh-ishi,Chitose Nakao,Yuzo Sato,Hideki Ohno +7 more
TL;DR: The results suggest that EC-SOD is distributed systemically in mice and that the physiological importance of this enzyme may be a compensatory adaptation to oxidative stress, particularly in lung and kidney.
Journal ArticleDOI
Endurance training improves the resistance of rat diaphragm to exercise-induced oxidative stress.
Shuji Oh-ishi,Takako Kizaki,Tomomi Ookawara,Tomonobu Sakurai,Tetsuya Izawa,Naokazu Nagata,Hideki Ohno +6 more
TL;DR: It is demonstrated that endurance training can upregulate certain antioxidant enzyme activities in rat diaphragm muscle, indicating the potential for improvement of the resistance to intracellular reactive oxygen species.
Journal ArticleDOI
EFFECTS OF ENDURANCE TRAINING ON SUPEROXIDE DISMUTASE ACTIVITY, CONTENT AND mRNA EXPRESSION IN RAT MUSCLE#
Shuji Oh-ishi,Takako Kizaki,Junichi Nagasawa,Tetsuya Izawa,Takao Komabayashi,Naokazu Nagata,Keiichiro Suzuki,Naoyuki Taniguchi,Hideki Ohno +8 more
TL;DR: The purpose of the present study was to investigate the changes in superoxide dismutase (SOD) isoenzyme activities, contents and mRNA expressions in rat skeletal muscle during endurance training and a single bout of exercise.