Sigrid Booms

TL;DR: Recommendations are made on whether there is a future for this therapeutic approach in Parkinson’s disease and also what any future PD trial involving GDNF and other GDNF family neurotrophic factors should consider in its design.

TL;DR: Examination of the cellular localization and pharmacokinetic properties of recombinant human CDNF (rhCDNF) protein after its infusion into rat brain parenchyma shows that after intrastriatal infusion the rhCDNF found in the SN is almost exclusively localized to the DA neurons, thus showing that it is retrogradely transported.

TL;DR: This study failed to provide evidence that fluoxetine enhances neuroplasticity, but data support other recent clinical studies suggesting that improvement of vision can be accomplished in adults with amblyopia.

TL;DR: While this study failed to provide evidence that fluoxetine enhances neuroplasticity, the data support the usefulness of perceptual training for vision improvement in adults with amblyopia.

TL;DR: In this article, the authors investigated whether event-related and oscillatory responses would be reduced for amblyopia and localized their cortical sources in higher-order visual areas and in parietal and prefrontal cortices.