S
Sijo Mathew
Researcher at North Dakota State University
Publications - 23
Citations - 577
Sijo Mathew is an academic researcher from North Dakota State University. The author has contributed to research in topics: Integrin & Villin. The author has an hindex of 13, co-authored 23 publications receiving 492 citations. Previous affiliations of Sijo Mathew include Central Food Technological Research Institute & Vanderbilt University.
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Journal ArticleDOI
Dimerization and Actin-bundling Properties of Villin and Its Role in the Assembly of Epithelial Cell Brush Borders
TL;DR: It is demonstrated for the first time that villin can bundle actin filaments using a single F-actin binding site, and a molecular mechanism for actin bundling by villin is provided, which could have wider implications for other actin cross-linking proteins that share a villin-like headpiece domain.
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Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration.
Sijo Mathew,Sudeep P. George,Yaohong Wang,Mohammad Rizwan Siddiqui,Kamalakkannan Srinivasan,Langzhu Tan,Seema Khurana +6 more
TL;DR: Data suggest that in colorectal carcinogenesis, elevation of c-Src or down-regulation of SHP-2 and/or PTP-PEST may promote cancer metastases and invasion by regulating villin-induced cell migration and cell invasion.
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The Quiet Renaissance of Protein Nuclear Magnetic Resonance
Paul J. Barrett,Jiang Chen,Min-Kyu Cho,Ji-Hun Kim,Zhenwei Lu,Sijo Mathew,Dungeng Peng,Yuanli Song,Wade D. Van Horn,Wade D. Van Horn,Tiandi Zhuang,Frank D. Sönnichsen,Charles R. Sanders +12 more
TL;DR: Recent advances in protein NMR that herald a renaissance in which a number of its most important applications reflect the broad problem-solving capability displayed by this method during its classical era during the 1970s and early 1980s are surveyed.
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Bicelles at low concentrations
TL;DR: The results suggest that the phase behavior of bicelles at low lipid-to-detergent ratios may be more complex than previously appreciated.
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Integrins in renal development
TL;DR: This review focuses on how integrins regulate renal development, which is mediated by numerous factors, including the communication of cells with their surrounding extracellular matrix.