The Quiet Renaissance of Protein Nuclear Magnetic Resonance
Paul J. Barrett,Jiang Chen,Min-Kyu Cho,Ji-Hun Kim,Zhenwei Lu,Sijo Mathew,Dungeng Peng,Yuanli Song,Wade D. Van Horn,Wade D. Van Horn,Tiandi Zhuang,Frank D. Sönnichsen,Charles R. Sanders +12 more
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TLDR
Recent advances in protein NMR that herald a renaissance in which a number of its most important applications reflect the broad problem-solving capability displayed by this method during its classical era during the 1970s and early 1980s are surveyed.Abstract:
From roughly 1985 through the start of the new millennium, the cutting edge of solution protein nuclear magnetic resonance (NMR) spectroscopy was to a significant extent driven by the aspiration to determine structures. Here we survey recent advances in protein NMR that herald a renaissance in which a number of its most important applications reflect the broad problem-solving capability displayed by this method during its classical era during the 1970s and early 1980s.read more
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Nuclear Magnetic Resonance
TL;DR: Emsley and Waugh as mentioned in this paper published the Guide to the NMR Empirical Method A Workbook, which is based on the Bible jun.. Pp. xi + 305.
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Molecular basis of MAP kinase regulation
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TL;DR: A review of recent crystal structures of MAPK:KIM‐peptide complexes and how residues outside the canonical KIM motif interact with specific MAPKs and contribute further to MAPK selectivity and signaling pathway fidelity is focused on.
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[Discovering high-affinity ligands for proteins: SAR by NMR].
Shinji Kamisuki,Motonari Uesugi +1 more
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Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR
Rina Rosenzweig,Lewis E. Kay +1 more
TL;DR: Methyl-TROSY (transverse relaxation optimized spectroscopy) NMR is highlighted, which enables the study of such large systems, and it is shown how this emerging technique contributes to an understanding of cellular function and the role of molecular plasticity in regulating an array of biochemical activities.
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Two-Dimensional NMR Lineshape Analysis
TL;DR: A more accurate and convenient method for the analysis of NMR titration experiments, based on the direct quantum mechanical simulation and fitting of entire two-dimensional experiments, is introduced, which is implemented in a new software tool, TITAN (TITration ANalysis).
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