S
Silvana van Koningsbruggen
Researcher at University of Dundee
Publications - 5
Citations - 1695
Silvana van Koningsbruggen is an academic researcher from University of Dundee. The author has contributed to research in topics: Gene & Nucleolus. The author has an hindex of 3, co-authored 4 publications receiving 1510 citations. Previous affiliations of Silvana van Koningsbruggen include Wellcome Trust.
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The multifunctional nucleolus
TL;DR: Although the nucleolus is primarily associated with ribosome biogenesis, several lines of evidence now show that it has additional functions, such as regulation of mitosis, cell-cycle progression and proliferation, many forms of stress response and biogenesis of multiple ribonucleoprotein particles.
Journal ArticleDOI
High-resolution whole-genome sequencing reveals that specific chromatin domains from most human chromosomes associate with nucleoli.
Silvana van Koningsbruggen,Marek Gierlinski,Pieta Schofield,David M. A. Martin,Geoffrey J. Barton,Yavuz Ariyurek,Johan T. den Dunnen,Angus I. Lamond +7 more
TL;DR: This work presents a genomewide, high-resolution study of nucleolar-associated chromatin using comparative genome hybridization, deep sequencing, and photoactivation microscopy, and shows specific regions from most chromosomes associate with nucleoli.
Journal ArticleDOI
Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors.
Motoharu Ono,Kayo Yamada,Fabio Avolio,Michelle S. Scott,Silvana van Koningsbruggen,Geoffrey J. Barton,Angus I. Lamond +6 more
TL;DR: It is demonstrated that this novel vector system (snoMEN) can deliver effective, sequence-specific knock down of endogenous cellular genes as well as GFP and GFP-fusion proteins.
Journal Article
Protein dynamics in the cell nucleus
Angus I. Lamond,F. M. Boivert,M. Ono,Laura Trinkle-Mulcahy,Silvana van Koningsbruggen,David Llères,Jens S. Andersen,Matthias Mann +7 more
Hematopoietic stem cell transplantation in a patient with proteasome-associated autoinflammatory syndrome (PRAAS)
Dorit Verhoeven,Dieneke Schonenberg-Meinema,Erich Ebstein,J. J. Papendorf,Paul A. Baars,Ester M. M. van Leeuwen,Machiel H. Jansen,Arjan C. Lankester,M. Burg,Sandrine Florquin,Saskia M. Maas,Silvana van Koningsbruggen,J. Merlijn van den Berg,Taco W. Kuijpers +13 more
TL;DR: This book aims to provide a history of web exceptionalism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “Web 2.0” began to circulate.