Simon Brown

TL;DR: Exposing the mesothelial lining of the body cavity of mice to long multiwalled carbon nanotubes results in asbestos-like, length-dependent, pathogenic behaviour, including inflammation and the formation of lesions known as granulomas.

TL;DR: It is proposed that CD31 (also known as platelet-endothelial cell adhesion molecule-1, PECAM-1) is an example of a cell-surface molecule that prevents phagocyte ingestion of closely apposed viable cells by transmitting ‘detachment’ signals, and which changes function on apoptosis, promoting tethering of dying cells to phagocytes.

TL;DR: Observations indicate that neutrophils from SLE patients have a reduced ability to be recognized and removed by the C1q/calreticulin/CD91-mediated apoptotic pathway, despite the presence of main apoptotic recognition partners.

TL;DR: Good agreement is found between the observations and the simulations but not with the classical continuum model, attributed to the faceted nature of the particles.

TL;DR: In this article, a method of forming a conducting nanowire between two contacts on a substrate surface is proposed, where a plurality of nanoparticles are deposited on the substrate in the region between the contacts, and the single nanowires running substantially between the two contacts is formed by either by monitoring the conduction between the contact and ceasing deposition at the onset of conduction, and/or modifying the substrate to achieve, or taking advantage of pre-existing topographical features which will cause the nanoparticles to form the nanowired.