S
Simon Leeson
Researcher at Betsi Cadwaladr University Health Board
Publications - 39
Citations - 2633
Simon Leeson is an academic researcher from Betsi Cadwaladr University Health Board. The author has contributed to research in topics: Colposcopy & Cervical screening. The author has an hindex of 14, co-authored 37 publications receiving 2065 citations.
Papers
More filters
Journal ArticleDOI
Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.
Ian Jacobs,Ian Jacobs,Ian Jacobs,Usha Menon,Andy Ryan,Aleksandra Gentry-Maharaj,Matthew Burnell,Jatinderpal Kalsi,Nazar Najib Amso,Sophia Apostolidou,Elizabeth Benjamin,Derek Cruickshank,Danielle N. Crump,Susan K Davies,Anne Dawnay,Stephen Dobbs,Gwendolen Fletcher,Jeremy Ford,Jeremy Ford,Keith M. Godfrey,Richard Gunu,Mariam Habib,Mariam Habib,Rachel Hallett,Rachel Hallett,Jonathan Herod,Howard Jenkins,Chloe Karpinskyj,Simon Leeson,Sara Lewis,William R. Liston,Alberto Lopes,Tim Mould,Tim Mould,John Murdoch,David H. Oram,Dustin J. Rabideau,K. Reynolds,Ian Scott,Mourad W. Seif,Mourad W. Seif,A. Sharma,A. Sharma,Naveena Singh,Julie Taylor,Fiona Warburton,Fiona Warburton,Martin Widschwendter,Karin Williamson,Robert Woolas,Robert Woolas,Lesley Fallowfield,Alistair McGuire,Stuart Campbell,Mahesh K. B. Parmar,Steven J. Skates +55 more
TL;DR: Although the mortality reduction was not significant in the primary analysis, it was noted a significant mortality reduction with MMS when prevalent cases were excluded, and encouraging evidence of a mortality reduction in years 7–14 was noted.
Journal ArticleDOI
Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: Results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
Usha Menon,Aleksandra Gentry-Maharaj,Rachel Hallett,Andy Ryan,Matthew Burnell,A. Sharma,Sara Lewis,Susan Davies,Susan Philpott,Alberto Lopes,Keith M. Godfrey,David H. Oram,Jonathan Herod,Karin Williamson,Mourad W Seif,Ian A Scott,Tim Mould,Robert Woolas,John Murdoch,Stephen Dobbs,Nazar Najib Amso,Simon Leeson,Derek Cruickshank,Alistair McGuire,Stuart Campbell,Lesley Fallowfield,Naveena Singh,Anne Dawnay,Steven J. Skates,Mahesh K. B. Parmar,Ian Jacobs +30 more
TL;DR: The United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) as mentioned in this paper was a randomized controlled trial designed to assess the effect of screening on mortality, and the outcome of the initial screening was summarised in the report.
Journal ArticleDOI
Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.
Usha Menon,Aleksandra Gentry-Maharaj,Matthew Burnell,Naveena Singh,Andy Ryan,Chloe Karpinskyj,Giulia Carlino,Julie Taylor,Susan K. Massingham,Maria Raikou,Jatinderpal Kalsi,Robert Woolas,Ranjit Manchanda,Rupali Arora,Laura Casey,Anne Dawnay,Stephen Dobbs,Simon Leeson,Tim Mould,Mourad W Seif,Aarti Sharma,Karin Williamson,Yiling Liu,Lesley Fallowfield,Alistair McGuire,Stuart Campbell,Steven J. Skates,Ian Jacobs,Mahesh K.B. Parmar +28 more
TL;DR: The UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) as discussed by the authors was a randomized controlled trial to determine if population screening can reduce deaths due to the disease.
Journal ArticleDOI
Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis.
Marc Arbyn,Charles W.E. Redman,Freija Verdoodt,Maria Kyrgiou,Menelaos Tzafetas,Sadaf Ghaem-Maghami,Karl Ulrich Petry,Simon Leeson,Christine Bergeron,Pekka Nieminen,Jean Gondry,Olaf Reich,Esther L. Moss +12 more
TL;DR: The risk of residual or recurrent CIN2+ is significantly greater with involved margins on excisional treatment; however, high-risk HPV post-treatment predicts treatment failure more accurately than margin status.
Journal ArticleDOI
Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort
Ian Jacobs,Aleksandra Gentry-Maharaj,Matthew Burnell,Ranjit Manchanda,Naveena Singh,A. Sharma,Andrew M. Ryan,Mourad W Seif,Nazar Najib Amso,Gillian Turner,Carol Brunell,Gwendolen Fletcher,Rani Rangar,Kathy Ford,Keith M. Godfrey,Alberto Lopes,David H. Oram,Jonathan Herod,Karin Williamson,Ian A Scott,Howard Jenkins,Tim Mould,Robert Woolas,John Murdoch,Stephen Dobbs,Simon Leeson,Derek Cruickshank,Steven J. Skates,Lesley Fallowfield,Mahesh K. B. Parmar,Stuart Campbell,Usha Menon +31 more
TL;DR: The findings show that TVS screening for endometrial cancer has good sensitivity in postmenopausal women, and the burden of diagnostic procedures and false-positive results can be reduced by limiting screening to a higher-risk group.