S
Simon M. Laws
Researcher at Edith Cowan University
Publications - 209
Citations - 6944
Simon M. Laws is an academic researcher from Edith Cowan University. The author has contributed to research in topics: Cognitive decline & Dementia. The author has an hindex of 40, co-authored 176 publications receiving 5645 citations. Previous affiliations of Simon M. Laws include University of Western Australia & Centre for Mental Health.
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Journal ArticleDOI
Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease
James D. Doecke,James D. Doecke,Simon M. Laws,Simon M. Laws,Noel G. Faux,Noel G. Faux,William Wilson,Samantha C. Burnham,Chiou Peng Lam,Alinda Mondal,Alinda Mondal,Justin Bedo,Ashley I. Bush,Ashley I. Bush,Belinda M. Brown,Belinda M. Brown,Karl De Ruyck,Karl De Ruyck,Kathryn A. Ellis,Christopher Fowler,Veer Bala Gupta,Veer Bala Gupta,Richard Head,S. Lance Macaulay,Kelly K. Pertile,Christopher C. Rowe,Alan Rembach,Mark Rodrigues,Mark Rodrigues,Rebecca L. Rumble,Cassandra Szoeke,Kevin Taddei,Kevin Taddei,Tania Taddei,Tania Taddei,Brett Trounson,David Ames,Colin L. Masters,Colin L. Masters,Ralph N. Martins,Ralph N. Martins +40 more
TL;DR: This study identified a panel of plasma biomarkers that distinguish individuals with AD from cognitively healthy control subjects with high sensitivity and specificity.
Journal ArticleDOI
Frontotemporal lobar degeneration
Janine Diehl-Schmid,Manuela Neumann,Simon M. Laws,Robert Perneczky,Timo Grimmer,Adrian Danek,Alexander Kurz,Matthias Riemenschneider,Hans Förstl +8 more
Journal ArticleDOI
Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription.
TL;DR: The genetic and biochemical evidence supporting the hypothesis that regulation of apoE protein levels may contribute to the risk of AD is reviewed, distinct from the well known polymorphisms at the ɛ2/ɚ3/ɛ4 locus.
Journal ArticleDOI
Bone mineral density, adiposity, and cognitive functions
Hamid R. Sohrabi,Hamid R. Sohrabi,Kristyn A. Bates,Michael Weinborn,Romola S. Bucks,Stephanie R. Rainey-Smith,Mark Rodrigues,Sabine Bird,Belinda M. Brown,John Beilby,Matthew A. Howard,Arthur Criddle,Megan Wraith,Kevin Taddei,Georgia Martins,Athena Paton,Tejal M. Shah,Satvinder S. Dhaliwal,Pankaj Mehta,Jonathan K. Foster,Ian Martins,Nicola T. Lautenschlager,Nicola T. Lautenschlager,Francis Mastaglia,Simon M. Laws,Ralph N. Martins,Ralph N. Martins +26 more
TL;DR: It is found that BMD and lean body mass, as measured using DXA were significant predictors of episodic memory and List A learning from California Verbal Learning Test both at baseline and at follow up assessment.
Journal ArticleDOI
The Guinea Pig as a Model for Sporadic Alzheimer’s Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes
Mathew J. Sharman,Mathew J. Sharman,Seyyed Hani Moussavi Nik,Mengqi M. Chen,Daniel Ong,Linda K. Wijaya,Simon M. Laws,Kevin Taddei,Kevin Taddei,Kevin Taddei,Morgan Newman,Michael Lardelli,Ralph N. Martins,Ralph N. Martins,Ralph N. Martins,Giuseppe Verdile,Giuseppe Verdile,Giuseppe Verdile +17 more
TL;DR: Guinea pigs represent a superior rodent model for analysis of the impact of dietary factors such as cholesterol on the regulation of AD-related genes, and it is concluded that AD- related genes are highly conserved and more similar to human than the rat or mouse.