S
Siu-Pok Yee
Researcher at University of Connecticut Health Center
Publications - 75
Citations - 3679
Siu-Pok Yee is an academic researcher from University of Connecticut Health Center. The author has contributed to research in topics: Transgene & Phosphorylation. The author has an hindex of 31, co-authored 69 publications receiving 3413 citations. Previous affiliations of Siu-Pok Yee include University of Western Ontario & Mount Sinai Hospital.
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Journal ArticleDOI
The regulation of myogenin gene expression during the embryonic development of the mouse
Siu-Pok Yee,Peter W. J. Rigby +1 more
TL;DR: It is concluded that the proper regulation of myogenin requires a bHLH protein, most probably Myf-5, the only myogenic b HLH factor known to be present in the embryo at the time thatmyogenin is activated, and an RSRF-like binding activity.
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A Novel Nuclear Receptor Corepressor Complex, N-CoR, Contains Components of the Mammalian SWI/SNF Complex and the Corepressor KAP-1
TL;DR: The results suggest that N-CoR is found in distinct multiprotein complexes, which are involved in multiple pathways of transcriptional repression.
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Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides
Siu-Pok Yee,Philip E. Branton +1 more
TL;DR: Antisera prepared against synthetic peptides corresponding to the amino and carboxy termini of human adenovirus type 5 (Ad5) early region 1A (E1A) proteins indicated that Ad5 E1A proteins may function in a complex with cellular polypeptides which includes species of 105K, 68K, 65K, and possibly a large protein of greater than 250K
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Development of Heart Failure and Congenital Septal Defects in Mice Lacking Endothelial Nitric Oxide Synthase
TL;DR: The data demonstrate that eNOS plays an important role in normal heart development and results in heart failure and congenital septal defects during cardiac development, which is associated with increases in cardiomyocyte apoptosis.
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MicroRNA MiR-17 retards tissue growth and represses fibronectin expression
Sze Wan Shan,Daniel Y. Lee,Daniel Y. Lee,Zhaoqun Deng,Tatiana Shatseva,Zina Jeyapalan,Zina Jeyapalan,William W. Du,Yaou Zhang,Jim W. Xuan,Siu-Pok Yee,Siu-Pok Yee,Vinayakumar Siragam,Burton B. Yang,Burton B. Yang +14 more
TL;DR: It is shown that overexpression of miR-17 results in decreased cell adhesion, migration and proliferation, and the single miRNA expression assay may be evolved to allow the manipulation of individual miRNA functions in vitro and in vivo.